Epistasis
Humana Press
Chapter title |
Epistasis Analysis Using ReliefF
|
---|---|
Chapter number | 17 |
Book title |
Epistasis
|
Published in |
Methods in molecular biology, November 2014
|
DOI | 10.1007/978-1-4939-2155-3_17 |
Pubmed ID | |
Book ISBNs |
978-1-4939-2154-6, 978-1-4939-2155-3, 978-1-4939-2154-6, 978-1-4939-2155-3
|
Authors |
Jason H. Moore, Moore JH, Moore, Jason H. |
Abstract |
Here we introduce the ReliefF machine learning algorithm and some of its extensions for detecting and characterizing epistasis in genetic association studies. We provide a general overview of the method and then highlight some of the modifications that have greatly improved its power for genetic analysis. We end with a few examples of published studies of complex human diseases that have used ReliefF. |
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