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Preeclampsia

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Cover of 'Preeclampsia'

Table of Contents

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    Book Overview
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    Chapter 1 Diagnostic Imaging: Ultrasound
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    Chapter 2 Biomarker Immunoassays in the Diagnosis of Preeclampsia: Calculating the sFlt1/PlGF Ratio Using the Cobas®e 411 Analyser
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    Chapter 3 Assessing the Circulating Placental-Specific Anti-angiogenic Protein sFLT-1 e15a in Preeclampsia
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    Chapter 4 Role of Activin A in the Pathogenesis of Endothelial Cell Dysfunction in Preeclampsia
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    Chapter 5 Genetic Approaches in Preeclampsia
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    Chapter 6 Epigenetics and Preeclampsia: Programming of Future Outcomes
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    Chapter 7 Inflammatory and Immune System Markers
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    Chapter 8 Methods to Enrich Exosomes from Conditioned Media and Biological Fluids
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    Chapter 9 Isolation and Characterization of Extracellular Vesicles from Ex Vivo Cultured Human Placental Explants
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    Chapter 10 Optimized Specific Isolation of Placenta-Derived Exosomes from Maternal Circulation
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    Chapter 11 Proteomics Method to Identification of Protein Profiles in Exosomes
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    Chapter 12 Harvesting and Characterization of Syncytial Nuclear Aggregates Following Culture of First Trimester Human Placental Explants
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    Chapter 13 Use of GATA3 and TWIST1 Immunofluorescence Staining to Assess In Vitro Syncytial Fusion Index
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    Chapter 14 Ex Vivo Dual Perfusion of the Human Placenta: Disease Simulation, Therapeutic Pharmacokinetics and Analysis of Off-Target Effects
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    Chapter 15 Immunohistological Techniques
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    Chapter 16 Using a Next-Generation Sequencing Approach to Profile MicroRNAs from Human Origin
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    Chapter 17 Isolation and Purification of Villous Cytotrophoblast Cells from Term Human Placenta
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    Chapter 18 Analyzing Trophoblast Function Using Cell-Based Assays
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    Chapter 19 Isolation and Characterization of Mesenchymal Stem/Stromal Cells Derived from Human Third Trimester Placental Chorionic Villi and Decidua Basalis
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    Chapter 20 An Electrical Impedance-Based Assay to Examine Functions of Various Placental Cell Types In Vitro
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    Chapter 21 In Vitro Induction of Hypoxia/Reoxygenation on Placental Cells: A Suitable Model for Understanding Placental Diseases. - PubMed - NCBI
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    Chapter 22 Measurement of Oxidative Stress: Mitochondrial Function Using the Seahorse System
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    Chapter 23 Co-culture of H295R Adrenocortical Carcinoma and BeWo Choriocarcinoma Cells to Study Feto-placental Interactions: Focus on Estrogen Biosynthesis
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    Chapter 24 Placental Lipid Transport
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    Chapter 25 EG-VEGF Maintenance Over Early Gestation to Develop a Pregnancy-Induced Hypertensive Animal Model
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    Chapter 26 Real-Time Blood Pressure Recording Using Radiotelemetry in a Rat Model of Preeclampsia
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    Chapter 27 Phase I Pilot Clinical Trial of Antenatal Maternally Administered Melatonin to Decrease the Level of Oxidative Stress in Human Pregnancies Affected by Preeclampsia
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    Chapter 28 A Randomized Double-Blinded Placebo-Controlled Intervention Trial of Melatonin for the Prevention of Preeclampsia in Moderate- and High-Risk Women: The MELPOP Trial
Attention for Chapter 21: In Vitro Induction of Hypoxia/Reoxygenation on Placental Cells: A Suitable Model for Understanding Placental Diseases. - PubMed - NCBI
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Chapter title
In Vitro Induction of Hypoxia/Reoxygenation on Placental Cells: A Suitable Model for Understanding Placental Diseases. - PubMed - NCBI
Chapter number 21
Book title
Preeclampsia
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7498-6_21
Pubmed ID
Book ISBNs
978-1-4939-7497-9, 978-1-4939-7498-6
Authors

Lucas Sagrillo-Fagundes, Laetitia Laurent, Josianne Bienvenue-Pariseault, Cathy Vaillancourt, Sagrillo-Fagundes, Lucas, Laurent, Laetitia, Bienvenue-Pariseault, Josianne, Vaillancourt, Cathy

Abstract

Lack of blood flow and aberrant levels of oxygenation in placentas are recurrent in pregnancy diseases, such as preeclampsia. These alterations generate situations of hypoxia and hypoxia/reoxygenation (H/R) and consequent oxidative stress, increased cell death, and inflammation in trophoblasts. The models used to understand the effects of hypoxia and H/R on trophoblasts require a rather big structure. This chapter describes the details of a suitable and reasonable approach with hypoxia chambers to expose human placental trophoblasts to variable conditions of oxygenation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 17%
Student > Doctoral Student 2 11%
Student > Postgraduate 2 11%
Student > Ph. D. Student 2 11%
Researcher 2 11%
Other 2 11%
Unknown 5 28%
Readers by discipline Count As %
Medicine and Dentistry 4 22%
Biochemistry, Genetics and Molecular Biology 4 22%
Pharmacology, Toxicology and Pharmaceutical Science 2 11%
Immunology and Microbiology 1 6%
Agricultural and Biological Sciences 1 6%
Other 0 0%
Unknown 6 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#18,577,751
of 23,009,818 outputs
Outputs from Methods in molecular biology
#7,962
of 13,157 outputs
Outputs of similar age
#330,497
of 442,310 outputs
Outputs of similar age from Methods in molecular biology
#950
of 1,498 outputs
Altmetric has tracked 23,009,818 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,157 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
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We're also able to compare this research output to 1,498 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.