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Preeclampsia

Overview of attention for book
Cover of 'Preeclampsia'

Table of Contents

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    Book Overview
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    Chapter 1 Diagnostic Imaging: Ultrasound
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    Chapter 2 Biomarker Immunoassays in the Diagnosis of Preeclampsia: Calculating the sFlt1/PlGF Ratio Using the Cobas®e 411 Analyser
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    Chapter 3 Assessing the Circulating Placental-Specific Anti-angiogenic Protein sFLT-1 e15a in Preeclampsia
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    Chapter 4 Role of Activin A in the Pathogenesis of Endothelial Cell Dysfunction in Preeclampsia
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    Chapter 5 Genetic Approaches in Preeclampsia
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    Chapter 6 Epigenetics and Preeclampsia: Programming of Future Outcomes
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    Chapter 7 Inflammatory and Immune System Markers
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    Chapter 8 Methods to Enrich Exosomes from Conditioned Media and Biological Fluids
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    Chapter 9 Isolation and Characterization of Extracellular Vesicles from Ex Vivo Cultured Human Placental Explants
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    Chapter 10 Optimized Specific Isolation of Placenta-Derived Exosomes from Maternal Circulation
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    Chapter 11 Proteomics Method to Identification of Protein Profiles in Exosomes
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    Chapter 12 Harvesting and Characterization of Syncytial Nuclear Aggregates Following Culture of First Trimester Human Placental Explants
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    Chapter 13 Use of GATA3 and TWIST1 Immunofluorescence Staining to Assess In Vitro Syncytial Fusion Index
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    Chapter 14 Ex Vivo Dual Perfusion of the Human Placenta: Disease Simulation, Therapeutic Pharmacokinetics and Analysis of Off-Target Effects
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    Chapter 15 Immunohistological Techniques
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    Chapter 16 Using a Next-Generation Sequencing Approach to Profile MicroRNAs from Human Origin
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    Chapter 17 Isolation and Purification of Villous Cytotrophoblast Cells from Term Human Placenta
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    Chapter 18 Analyzing Trophoblast Function Using Cell-Based Assays
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    Chapter 19 Isolation and Characterization of Mesenchymal Stem/Stromal Cells Derived from Human Third Trimester Placental Chorionic Villi and Decidua Basalis
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    Chapter 20 An Electrical Impedance-Based Assay to Examine Functions of Various Placental Cell Types In Vitro
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    Chapter 21 In Vitro Induction of Hypoxia/Reoxygenation on Placental Cells: A Suitable Model for Understanding Placental Diseases. - PubMed - NCBI
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    Chapter 22 Measurement of Oxidative Stress: Mitochondrial Function Using the Seahorse System
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    Chapter 23 Co-culture of H295R Adrenocortical Carcinoma and BeWo Choriocarcinoma Cells to Study Feto-placental Interactions: Focus on Estrogen Biosynthesis
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    Chapter 24 Placental Lipid Transport
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    Chapter 25 EG-VEGF Maintenance Over Early Gestation to Develop a Pregnancy-Induced Hypertensive Animal Model
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    Chapter 26 Real-Time Blood Pressure Recording Using Radiotelemetry in a Rat Model of Preeclampsia
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    Chapter 27 Phase I Pilot Clinical Trial of Antenatal Maternally Administered Melatonin to Decrease the Level of Oxidative Stress in Human Pregnancies Affected by Preeclampsia
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    Chapter 28 A Randomized Double-Blinded Placebo-Controlled Intervention Trial of Melatonin for the Prevention of Preeclampsia in Moderate- and High-Risk Women: The MELPOP Trial
Attention for Chapter 23: Co-culture of H295R Adrenocortical Carcinoma and BeWo Choriocarcinoma Cells to Study Feto-placental Interactions: Focus on Estrogen Biosynthesis
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Chapter title
Co-culture of H295R Adrenocortical Carcinoma and BeWo Choriocarcinoma Cells to Study Feto-placental Interactions: Focus on Estrogen Biosynthesis
Chapter number 23
Book title
Preeclampsia
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7498-6_23
Pubmed ID
29197012
Book ISBNs
978-1-4939-7497-9, 978-1-4939-7498-6
Authors

Andrée-Anne Hudon Thibeault, J. Thomas Sanderson, Cathy Vaillancourt, Thibeault, Andrée-Anne Hudon, Sanderson, J. Thomas, Vaillancourt, Cathy

Abstract

Estrogens are produced in large amounts during pregnancy, as a result of a tightly regulated cooperation between the maternal and fetal adrenal cortex, which produce androgen precursors, and the placental villous trophoblast, which transforms these precursors into estrogens. These estrogens play an important role in proper placental function, in adaptation of the mother to pregnancy, as well as in adequate fetal development. Disruption of estrogen production is associated with poor pregnancy outcomes and fetal malformation or altered fetal programming. Pregnant women may be exposed to endocrine disruptors from environmental sources or medications, and it is crucial to study the effects of such compounds on feto-placental steroidogenesis. The H295R/BeWo co-culture model offers the opportunity to study these interactions, by making it possible to evaluate the effects of chemical exposures on androgen and estrogen biosynthesis, as well as on various other aspects of feto-placental communication.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 6 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 50%
Student > Bachelor 1 17%
Unknown 2 33%
Readers by discipline Count As %
Medicine and Dentistry 2 33%
Nursing and Health Professions 1 17%
Pharmacology, Toxicology and Pharmaceutical Science 1 17%
Unknown 2 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 July 2018.
All research outputs
#20,453,782
of 23,009,818 outputs
Outputs from Methods in molecular biology
#9,941
of 13,157 outputs
Outputs of similar age
#378,135
of 442,310 outputs
Outputs of similar age from Methods in molecular biology
#1,193
of 1,498 outputs
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So far Altmetric has tracked 13,157 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 1,498 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.

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