Chapter title |
The Validity of Bioelectrical Impedance Analysis to Measure Body Composition in Phenylketonuria
|
---|---|
Chapter number | 75 |
Book title |
JIMD Reports, Volume 42
|
Published in |
JIMD Reports, January 2017
|
DOI | 10.1007/8904_2017_75 |
Pubmed ID | |
Book ISBNs |
978-3-66-258364-7, 978-3-66-258365-4
|
Authors |
Maureen Evans, Kay Nguo, Avihu Boneh, Helen Truby, Evans, Maureen, Nguo, Kay, Boneh, Avihu, Truby, Helen |
Abstract |
To compare the measurement of total body water (TBW) and fat-free mass (FFM) using the criterion method of deuterium dilution space ((2)H2O) with bioelectrical impedance analysis (BIA) using a portable QuadScan 4000, Bodystat(®) in children and adolescents with phenylketonuria (PKU). Sixteen patients with PKU, median age is 12.5 (range 5-20.6) years, were recruited into this cross-sectional study. TBW was measured by both deuterium dilution and BIA on the same occasion as per a standard protocol. FFM was estimated from predictive equations. There was no significant difference between TBWDeut and TBWBIA (p = 0.344) or FFMDeut and FFMBIA (p = 0.111). TBWDeut and TBWBIA were highly correlated (r = 0.990, p < 0.0001), as were FFMDeut and FFMBIA (r = 0.984, p < 0.0001). Bland-Altman plots demonstrated that there was no proportional bias between the criterion method, TBWDeut, and the test method TBWBIA, in estimating TBW (β = -0.056, adjusted r (2) = 0.069, p = 0.169) or FFM (β = -0.089, adjusted r (2) = 0.142, p = 0.083). Our results suggest that when compared with the criterion method, the QuadScan 4000, Bodystat(®) can reliably be used to predict TBW and FFM in patients with PKU. We suggest that due to the portability and non-invasive approach, this method can reliably be used to monitor body composition in the outpatient clinic setting, to further improve the monitoring and assessment of nutritional status in PKU. |
X Demographics
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 27 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 5 | 19% |
Student > Bachelor | 3 | 11% |
Student > Postgraduate | 3 | 11% |
Researcher | 3 | 11% |
Student > Doctoral Student | 2 | 7% |
Other | 6 | 22% |
Unknown | 5 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Nursing and Health Professions | 6 | 22% |
Sports and Recreations | 4 | 15% |
Unspecified | 2 | 7% |
Medicine and Dentistry | 2 | 7% |
Business, Management and Accounting | 1 | 4% |
Other | 5 | 19% |
Unknown | 7 | 26% |