Chapter title |
Interleukin-1 and its inhibitors: implications for disease biology and therapy.
|
---|---|
Chapter number | 3 |
Book title |
Cytokines: Interleukins and Their Receptors
|
Published in |
Cancer treatment and research, January 1995
|
DOI | 10.1007/978-1-4613-1241-3_3 |
Pubmed ID | |
Book ISBNs |
978-1-4612-8528-1, 978-1-4613-1241-3
|
Authors |
Zeev Estrov, Razelle Kurzrock, Moshe Talpaz, Estrov, Zeev, Kurzrock, Razelle, Talpaz, Moshe |
Abstract |
IL-1 alpha and IL-1 beta are polypeptide hormones that exhibit a broad spectrum of beneficial and harmful biologic activities. Clinical trials designed to benefit from its stimulatory effects on human hematopoiesis and from its role in improving host defenses, are being currently conducted. Other in vivo studies, using IL-1 inhibitors with an attempts to block the detrimental effects of IL-1, are underway. Because of the multifunctional effects of IL-1 in human physiology and its pathogenetic role in several diseases, the capability to control the effects of IL-1 may prove to be a useful tool in medical practice. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 4% |
United States | 1 | 4% |
Unknown | 23 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 4 | 16% |
Professor | 3 | 12% |
Other | 1 | 4% |
Student > Bachelor | 1 | 4% |
Student > Ph. D. Student | 1 | 4% |
Other | 3 | 12% |
Unknown | 12 | 48% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 4 | 16% |
Agricultural and Biological Sciences | 3 | 12% |
Biochemistry, Genetics and Molecular Biology | 3 | 12% |
Decision Sciences | 1 | 4% |
Neuroscience | 1 | 4% |
Other | 0 | 0% |
Unknown | 13 | 52% |