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Hemorrhagic Fever Viruses

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Cover of 'Hemorrhagic Fever Viruses'

Table of Contents

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    Book Overview
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    Chapter 1 Global Spread of Hemorrhagic Fever Viruses: Predicting Pandemics
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    Chapter 2 An Approach to the Identification and Phylogenetic Analysis of Emerging and Hemorrhagic Fever Viruses
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    Chapter 3 Preliminary Classification of Novel Hemorrhagic Fever-Causing Viruses Using Sequence-Based PAirwise Sequence Comparison (PASC) Analysis
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    Chapter 4 Epidemiological Surveillance of Viral Hemorrhagic Fevers With Emphasis on Clinical Virology
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    Chapter 5 Diagnostics for Lassa Fever: Detecting Host Antibody Responses
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    Chapter 6 Sampling Design and Mosquito Trapping for Surveillance of Arboviral Activity
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    Chapter 7 Epidemiological Surveillance of Rodent-Borne Viruses (Roboviruses)
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    Chapter 8 Entry Studies of New World Arenaviruses
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    Chapter 9 Studies of Lassa Virus Cell Entry
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    Chapter 10 A Cell-Cell Fusion Assay to Assess Arenavirus Envelope Glycoprotein Membrane-Fusion Activity
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    Chapter 11 Assays to Assess Arenaviral Glycoprotein Function
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    Chapter 12 Expression and X-Ray Structural Determination of the Nucleoprotein of Lassa Fever Virus
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    Chapter 13 Assays to Demonstrate the Roles of Arenaviral Nucleoproteins (NPs) in Viral RNA Synthesis and in Suppressing Type I Interferon
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    Chapter 14 Intracellular Detection of Viral Transcription and Replication Using RNA FISH
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    Chapter 15 Hemorrhagic Fever Virus Budding Studies
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    Chapter 16 Roles of Arenavirus Z Protein in Mediating Virion Budding, Viral Transcription-Inhibition and Interferon-Beta Suppression
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    Chapter 17 Structure–Function Assays for Crimean–Congo Hemorrhagic Fever Virus Polymerase
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    Chapter 18 Minigenome Systems for Filoviruses
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    Chapter 19 Establishment of Bisegmented and Trisegmented Reverse Genetics Systems to Generate Recombinant Pichindé Viruses
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    Chapter 20 Murine Models for Viral Hemorrhagic Fever
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    Chapter 21 Testing Experimental Therapies in a Guinea Pig Model for Hemorrhagic Fever
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    Chapter 22 A Primate Model for Viral Hemorrhagic Fever
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    Chapter 23 A Primary Human Liver Cell Culture Model for Hemorrhagic Fever Viruses
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    Chapter 24 Protocol for the Production of a Vaccine Against Argentinian Hemorrhagic Fever
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    Chapter 25 Detection of Virus-Antibody Immune Complexes in Secondary Dengue Virus Infection
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    Chapter 26 Future Approaches to DNA Vaccination Against Hemorrhagic Fever Viruses
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    Chapter 27 Identifying Restriction Factors for Hemorrhagic Fever Viruses: Dengue and Junín
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    Chapter 28 Determining the Virus Life-Cycle Stage Blocked by an Antiviral
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    Chapter 29 Retrovirus-Based Surrogate Systems for BSL-2 High-Throughput Screening of Antivirals Targeting BSL-3/4 Hemorrhagic Fever-Causing Viruses
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    Chapter 30 Protocols to Assess Coagulation Following In Vitro Infection with Hemorrhagic Fever Viruses
Attention for Chapter 3: Preliminary Classification of Novel Hemorrhagic Fever-Causing Viruses Using Sequence-Based PAirwise Sequence Comparison (PASC) Analysis
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Chapter title
Preliminary Classification of Novel Hemorrhagic Fever-Causing Viruses Using Sequence-Based PAirwise Sequence Comparison (PASC) Analysis
Chapter number 3
Book title
Hemorrhagic Fever Viruses
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-6981-4_3
Pubmed ID
Book ISBNs
978-1-4939-6980-7, 978-1-4939-6981-4
Authors

Yīmíng Bào, Jens H. Kuhn

Abstract

During the last decade, genome sequence-based classification of viruses has become increasingly prominent. Viruses can be even classified based on coding-complete genome sequence data alone. Nevertheless, classification remains arduous as experts are required to establish phylogenetic trees to depict the evolutionary relationships of such sequences for preliminary taxonomic placement. Pairwise sequence comparison (PASC) of genomes is one of several novel methods for establishing relationships among viruses. This method, provided by the US National Center for Biotechnology Information as an open-access tool, circumvents phylogenetics, and yet PASC results are often in agreement with those of phylogenetic analyses. Computationally inexpensive, PASC can be easily performed by non-taxonomists. Here we describe how to use the PASC tool for the preliminary classification of novel viral hemorrhagic fever-causing viruses.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 2 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 2 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 1 50%
Researcher 1 50%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 1 50%
Agricultural and Biological Sciences 1 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2017.
All research outputs
#15,481,147
of 23,005,189 outputs
Outputs from Methods in molecular biology
#5,386
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Outputs of similar age
#269,666
of 442,254 outputs
Outputs of similar age from Methods in molecular biology
#596
of 1,498 outputs
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So far Altmetric has tracked 13,159 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
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