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Mendeley readers
Chapter title |
Searching for Correlations Between the Development of Neurodegenerative Hallmarks: Targeting Huntingtin as a Contributing Factor
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Chapter number | 24 |
Book title |
GeNeDis 2016
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Published in |
Advances in experimental medicine and biology, January 2017
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DOI | 10.1007/978-3-319-57379-3_24 |
Pubmed ID | |
Book ISBNs |
978-3-31-957378-6, 978-3-31-957379-3
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Authors |
Nelina P. Angelova |
Abstract |
This paper aims to study four general hallmarks of neurodegeneration and the correlations between them, with emphasis on the huntingtin (htt) interactions contributing to their prevention or promotion in its wild-type and mutated forms. Most of the neurodegenerative diseases share same or similar cell dysfunctions and huntingtin seems to associate in an polyglutamine-length dependent manner with components of the mechanisms that can go impaired. Therefore, the protein is proposed as contributing factor to the development of selective neurodegeneration. |
Mendeley readers
The data shown below were compiled from readership statistics for 1 Mendeley reader of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 1 | 100% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 1 | 100% |