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Neurotoxicity of Metals

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Attention for Chapter 2: Manganese and Developmental Neurotoxicity
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Chapter title
Manganese and Developmental Neurotoxicity
Chapter number 2
Book title
Neurotoxicity of Metals
Published in
Advances in neurobiology, January 2017
DOI 10.1007/978-3-319-60189-2_2
Pubmed ID
Book ISBNs
978-3-31-960188-5, 978-3-31-960189-2
Authors

Roberto Lucchini, Donatella Placidi, Giuseppa Cagna, Chiara Fedrighi, Manuela Oppini, Marco Peli, Silvia Zoni

Abstract

Manganese (Mn) is an essential metal that plays a fundamental role for brain development and functioning. Environmental exposure to Mn may lead to accumulation in the basal ganglia and development of Parkinson-like disorders. The most recent research is focusing on early-life overexposure to Mn and the potential vulnerability of younger individuals to Mn toxicity also in regard to cognitive and executive functions through the involvement of the frontal cortex.Neurodevelopmental disturbances are increasing in the society, and understanding the potential role of environmental determinants is a key for prevention. Therefore, assessing the environmental sources of Mn exposure and the mechanisms of developmental neurotoxicity and defining appropriate biomarkers of exposure and early functional alterations represent key issues to improve and address preventive strategies. These themes will be reviewed in this chapter.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 125 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 125 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 14%
Researcher 14 11%
Student > Ph. D. Student 13 10%
Student > Bachelor 11 9%
Student > Doctoral Student 7 6%
Other 21 17%
Unknown 41 33%
Readers by discipline Count As %
Medicine and Dentistry 17 14%
Psychology 14 11%
Environmental Science 8 6%
Neuroscience 6 5%
Agricultural and Biological Sciences 5 4%
Other 30 24%
Unknown 45 36%