"Practically all effects of the benzodiazepines result from their actions on the ionotropic GABA(A) receptors in the central nervous system. Benzodiazepines do not activate GABA(A) receptors directly but they require GABA." https://t.co/E3cifmTQaS
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@DrMarinee Jesus H. Christ sis, shoot whoever wrote that question! U can rx ASA, NSAIDs, and acyclovir to ESRD patient (w dose adjustments). BZD, however can be a devil in this population. Kinetics appear favorable, given CYP metabolism, but ESRD patients
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@MallinsonT @ketaminh Does this help?? As always things seem a little more complicated than we think they are 😉 Anyhow, here‘s the publication: https://t.co/9nqgaVI450 https://t.co/TDh3Poh4tY
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The general pharmacokinetics of benzodiazepine. http://t.co/7dCIJGl6LB #BCACa20