Chapter title |
Metabolism in Immune Cell Differentiation and Function
|
---|---|
Chapter number | 1 |
Book title |
Immune Metabolism in Health and Tumor
|
Published in |
Advances in experimental medicine and biology, January 2017
|
DOI | 10.1007/978-94-024-1170-6_1 |
Pubmed ID | |
Book ISBNs |
978-9-40-241168-3, 978-9-40-241170-6
|
Authors |
Nicole M. Chapman, Sharad Shrestha, Hongbo Chi, Chapman, Nicole M., Shrestha, Sharad, Chi, Hongbo |
Abstract |
The immune system is a central determinant of organismal health. Functional immune responses require quiescent immune cells to rapidly grow, proliferate, and acquire effector functions when they sense infectious agents or other insults. Specialized metabolic programs are critical regulators of immune responses, and alterations in immune metabolism can cause immunological disorders. There has thus been growing interest in understanding how metabolic processes control immune cell functions under normal and pathophysiological conditions. In this chapter, we summarize how metabolic programs are tuned and what the physiological consequences of metabolic reprogramming are as they relate to immune cell homeostasis, differentiation, and function. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 3 | 17% |
Researcher | 2 | 11% |
Student > Postgraduate | 2 | 11% |
Student > Ph. D. Student | 2 | 11% |
Student > Doctoral Student | 1 | 6% |
Other | 3 | 17% |
Unknown | 5 | 28% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 4 | 22% |
Biochemistry, Genetics and Molecular Biology | 3 | 17% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 11% |
Immunology and Microbiology | 2 | 11% |
Environmental Science | 1 | 6% |
Other | 0 | 0% |
Unknown | 6 | 33% |