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Prodrugs

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Cover of 'Prodrugs'

Table of Contents

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    Book Overview
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    Chapter 1 A Case for Prodrugs
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    Chapter 2 Prodrug Approaches to Enhancing the Oral Delivery of Poorly Permeable Drugs
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    Chapter 3 Topical Delivery Using Prodrugs
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    Chapter 4 Prodrug approaches to ophthalmic drug delivery
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    Chapter 5 Overcoming Poor Aqueous Solubility of Drugs for Oral Delivery
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    Chapter 6 Prodrugs and Parenteral Drug Delivery
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    Chapter 7 Poly (ethylene glycol) Prodrugs: Altered Pharmacokinetics and Pharmacodynamics
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    Chapter 8 Prodrugs to Reduce Presystemic Metabolism
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    Chapter 9 Controlled Release — Small Molecules
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    Chapter 10 Controlled Release - Macromolecular Prodrugs
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    Chapter 11 Controlled Release - Proenzymes
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    Chapter 12 Targeting - Theoretical and Computational Models
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    Chapter 13 Targeting - Cancer — Small Molecules
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    Chapter 14 Monoclonal Antibody Drug Conjugates for Cancer Therapy
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    Chapter 15 Antibody-Directed Enzyme Prodrug Therapy
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    Chapter 16 Prodrugs for Liver-targeted Drug Delivery
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    Chapter 17 Prodrug Approaches for Drug Delivery to the Brain
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    Chapter 18 Lymphatic Absorption of Orally Administered Prodrugs
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    Chapter 19 Colonic Delivery
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    Chapter 20 Prodrugs of Carboxylic Acids
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    Chapter 21 Prodrugs of Alcohols and Phenols
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    Chapter 22 Prodrugs of Amines
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    Chapter 23 Prodrugs of Amides, Imides and Other NH-acidic Compounds
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    Chapter 24 Prodrugs of Benzamidines
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    Chapter 25 Prodrugs of Phosphonates, Phosphinates, and Phosphates
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    Chapter 26 Functional Group Approaches to Prodrugs: Functional Groups in Peptides
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    Chapter 27 Macromolecular Prodrugs of Small Molecules
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    Chapter 28 Miscellaneous Functional Groups
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    Chapter 29 Prodrugs: Absorption, Distribution, Metabolism, Excretion (ADME) Issues
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    Chapter 30 Prodrugs
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    Chapter 31 Safety Assessment of Prodrugs
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    Chapter 32 Toxicological Issues with Pivalate Prodrugs
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    Chapter 33 Case Study: Adefovir Dipivoxil: An Oral Prodrug of Adefovir
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    Chapter 34 Case Study: Amifostine: (Ethyol®)
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    Chapter 35 Case Study: Capecitabine: A Prodrug of 5-Fluorouracil
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    Chapter 36 Case Study: Cefditoren Pivoxil: An Oral Prodrug of Cefditoren
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    Chapter 37 Case Study: Cefuroxime Axetil: An Oral Prodrug of Cefuroxime
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    Chapter 38 Case Study: Clindamycin 2-Phosphate, A Prodrug of Clindamycin
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    Chapter 39 Case Study: Enalapril: A Prodrug of Enalaprilat
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    Chapter 40 Case Study: Famciclovir: A Prodrug of Penciclovir
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    Chapter 41 Case Study: Fosamprenavir: A Prodrug of Amprenavir
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    Chapter 42 Case Study: Fosinopril
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    Chapter 43 Case Study: Fosphenytoin: A Prodrug of Phenytoin
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    Chapter 44 Case Study: Irinotecan (CPT-11), A Water-soluble Prodrug of SN-38
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    Chapter 45 Case Study: Latanoprost: Isopropylester of a Prostaglandin F2α Analog
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    Chapter 46 Case Study: Moexipril Hydrochloride: A Prodrug of Moexiprilat
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    Chapter 47 Case Study: Mycophenolate Mofetil
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    Chapter 48 Case Study: Olmesartan Medoxomil: A Prodrug of Olmesartan
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    Chapter 49 Case Study: Omeprazole (Prilosec®)
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    Chapter 50 Case Study: Oseltamivir: An Orally Bioavailable Ester Prodrug of Oseltamivir Carboxylate
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    Chapter 51 Case Study: Parecoxib: A Prodrug of Valdecoxib
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    Chapter 52 Case Study: Tenofovir Disoproxil Fumarate: An Oral Prodrug of Tenofovir
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    Chapter 53 Case Study: Travoprost: A Potent PGF2α Analog
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    Chapter 54 Case Study: Valacyclovir: A Prodrug of Acyclovir
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    Chapter 55 Case Study: Valganciclovir: A Prodrug of Ganciclovir
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    Chapter 56 Case Study: Vantin: A Prodrug of Cefpodoxime
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    Chapter 57 Case Study: Ximelagatran: A Double Prodrug of Melagatran
Attention for Chapter 20: Prodrugs of Carboxylic Acids
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Chapter title
Prodrugs of Carboxylic Acids
Chapter number 20
Book title
Prodrugs
Published by
Springer, New York, NY, January 2007
DOI 10.1007/978-0-387-49785-3_20
Book ISBNs
978-0-387-49782-2, 978-0-387-49785-3
Authors

Hans Maag, Maag, Hans

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 72 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 21%
Researcher 13 18%
Student > Master 8 11%
Other 5 7%
Student > Bachelor 4 6%
Other 11 15%
Unknown 16 22%
Readers by discipline Count As %
Chemistry 28 39%
Pharmacology, Toxicology and Pharmaceutical Science 6 8%
Biochemistry, Genetics and Molecular Biology 4 6%
Medicine and Dentistry 4 6%
Chemical Engineering 3 4%
Other 7 10%
Unknown 20 28%