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Human Retroviruses

Overview of attention for book
Cover of 'Human Retroviruses'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Virion Attachment and Entry: HIV gp120 Env Biotinylation, gp120 Env, or Integrin Ligand-Binding Assay
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    Chapter 2 CryoEM Analysis of Capsid Assembly and Structural Changes Upon Interactions with a Host Restriction Factor, TRIM5α
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    Chapter 3 The Fate of HIV-1 Capsid: A Biochemical Assay for HIV-1 Uncoating
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    Chapter 4 The Cyclosporin A Washout Assay to Detect HIV-1 Uncoating in Infected Cells
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    Chapter 5 Imaging HIV-1 Nuclear Pre-integration Complexes
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    Chapter 6 HIV-1 Reverse Transcription
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    Chapter 7 RNase H: Specificity, Mechanisms of Action, and Antiviral Target
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    Chapter 8 HIV-1 Chromatin, Transcription, and the Regulatory Protein Tat
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    Chapter 9 HIV-1 Rev Function and RNA Nuclear-Cytoplasmic Export.
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    Chapter 10 HIV-1 Accessory Proteins: Nef
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    Chapter 11 HIV-1 Accessory Proteins: VpR
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    Chapter 12 HIV-1 Accessory Proteins: Vpu and Vif.
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    Chapter 13 SIVSM/HIV-2 Vpx Proteins: Function and Uses in the Infection of Primary Myeloid Cells.
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    Chapter 14 Imaging of HIV Assembly and Release
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    Chapter 15 HIV-1 Isolation from Infected Peripheral Blood Mononuclear Cells
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    Chapter 16 Determination of HIV-1 Co-receptor Usage
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    Chapter 17 The Macrophage and HIV: Basic Concepts and Methodologies
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    Chapter 18 HIV infection of dendritic cells.
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    Chapter 19 Histocultures (Tissue Explants) in Human Retrovirology
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    Chapter 20 Single-Copy Quantification of HIV-1 in Clinical Samples.
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    Chapter 21 Quantification of Total HIV1-DNA in Peripheral Blood Mononuclear Cells
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    Chapter 22 HIV-1-Based Lentiviral Vectors
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    Chapter 23 Quantification of miRNA by Poly(A)-RT-qPCR Arrays and Verification of Target Sites in HIV-1 Using a One-LTR Infectious Molecular Clone
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    Chapter 24 Investigating human T cell lymphotropic retrovirus (HTLV) tax function with molecular and immunophenotypic techniques.
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    Chapter 25 Proviral Load Determination of HTLV-1 and HTLV-2 in Patients' Peripheral Blood Mononuclear Cells by Real-Time PCR.
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    Chapter 26 Quantitative Analysis of Human T-Lymphotropic Virus Type 1 (HTLV-1) Gene Expression Using Nucleo-Cytoplasmic Fractionation and Splice Junction-Specific Real-Time RT-PCR (qRT-PCR).
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    Chapter 27 Erratum To: Proviral Load Determination of HTLV-1 and HTLV-2 in Patients’ Peripheral Blood Mononuclear Cells by Real-Time PCR
Attention for Chapter 13: SIVSM/HIV-2 Vpx Proteins: Function and Uses in the Infection of Primary Myeloid Cells.
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  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

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Chapter title
SIVSM/HIV-2 Vpx Proteins: Function and Uses in the Infection of Primary Myeloid Cells.
Chapter number 13
Book title
Human Retroviruses
Published in
Methods in molecular biology, October 2013
DOI 10.1007/978-1-62703-670-2_13
Pubmed ID
24158821
Book ISBNs
978-1-62703-669-6, 978-1-62703-670-2
Authors

Berger G, Cimarelli A, Gregory Berger, Andrea Cimarelli, Berger, Gregory, Cimarelli, Andrea

Abstract

Vpx is coded almost exclusively by members of the SIVSM/HIV-2 lineage of primate lentiviruses, it is incorporated into virion particles and is thus present during the early phases of infection of target cells. While Vpx exerts no detectable function during the infection of most cell types, it potently counteracts a cellular restriction that targets incoming lentiviruses specifically in myeloid cells. As a consequence of this function, Vpx improves the efficiency of lentiviral infection of dendritic cells (DCs), macrophages, and monocytes. Here, we describe how the positive function exerted by Vpx during the early phases of infection of myeloid cells can be used to augment the efficiency of lentiviral vector-mediated gene transfer in these cells.

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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 2 7%
Researcher 2 7%
Student > Ph. D. Student 1 4%
Student > Bachelor 1 4%
Student > Master 1 4%
Other 0 0%
Unknown 21 75%
Readers by discipline Count As %
Agricultural and Biological Sciences 2 7%
Immunology and Microbiology 2 7%
Medicine and Dentistry 2 7%
Unknown 22 79%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2014.
All research outputs
#15,300,431
of 22,755,127 outputs
Outputs from Methods in molecular biology
#5,313
of 13,089 outputs
Outputs of similar age
#130,794
of 212,615 outputs
Outputs of similar age from Methods in molecular biology
#11
of 38 outputs
Altmetric has tracked 22,755,127 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,089 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 212,615 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.

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