Chapter title |
Postinduction and preremission chemotherapy alternatives for adult AML: three multicenter studies of the AML Cooperative Group.
|
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Chapter number | 10 |
Book title |
Acute Leukemias
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Published in |
Haematology and blood transfusion, January 1987
|
DOI | 10.1007/978-3-642-71213-5_10 |
Pubmed ID | |
Book ISBNs |
978-3-54-016556-9, 978-3-64-271213-5
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Authors |
Büchner, T, Hiddemann, W, Urbanitz, D, Kreutzmann, H, Maschmeyer, G, Wendt, F, Kuse, R, Mohr, A, Gassmann, W, Löffler, H, Büchner, T., Hiddemann, W., Urbanitz, D., Kreutzmann, H., Maschmeyer, G., Wendt, F., Kuse, R., Mohr, A., Gassmann, W., Löffler, H., Straif, K., Vaupel, H. A., König, H. J., Rühl, H., Nowrousian, M. R., Fuhr, H. G., Zeile, G., von Paleske, A., Schwamborn, J., Fülle, H. H., Bartels, H., Emmerich, B., Lengfelder, E., Donhuijsen-Ant, R., Ho, A., Mainzer, K., Köppler, H., Thiel, E., Middelhoff, G., Nowicki, L., Zurborn, K. H., Siegert, W., Planker, M., Augener, W., Heinecke, A. |
Abstract |
Major chemotherapeutic alternatives for AML have been implemented and compared in three multicenter studies, including a total of 877 adult patients of all ages. The results strongly suggest that myelosuppressive postinduction treatment is a prerequisite for the achievement of long-term remissions. In addition, it was possible to establish an important antileukemic effect of monthly maintenance chemotherapy. Initial results from an intensive two-course preremission therapy concept revealed good practicability and acceptable toxicity, as well as promising response and remission durations by this new approach. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 3 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 1 | 33% |
Lecturer | 1 | 33% |
Unknown | 1 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Nursing and Health Professions | 1 | 33% |
Agricultural and Biological Sciences | 1 | 33% |
Unknown | 1 | 33% |