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Dietary Phytochemicals in Cancer Prevention and Treatment

Overview of attention for book
Cover of 'Dietary Phytochemicals in Cancer Prevention and Treatment'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Chemoprevention of lung cancer by isothiocyanates.
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    Chapter 2 Isothiocyanates as Inhibitors of Esophageal Cancer
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    Chapter 3 Plant Phenolics as Potential Cancer Prevention Agents
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    Chapter 4 Cancer Chemoprevention by Polyphenols in Green Tea and Artichoke
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    Chapter 5 Effects of Tea on Carcinogenesis in Animal Models and Humans
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    Chapter 6 Estrogens, Phytoestrogens, and Breast Cancer
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    Chapter 7 Soy Isoflavonoids and Cancer Prevention
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    Chapter 8 Quercetin as a Modulator of the Cellular Neoplastic Phenotype
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    Chapter 9 Effects of Monoterpenes and Mevinolin on Murine Colon Tumor CT-26 in Vitro and its Hepatic “Metastases” in Vitro
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    Chapter 10 Antitumorigenic effects of limonene and perillyl alcohol against pancreatic and breast cancer.
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    Chapter 11 Monoterpenes as Regulators of Malignant Cell Proliferation
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    Chapter 12 Organosulfur Compounds and Cancer
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    Chapter 13 Recent Results in the Organosulfur and Organoselenium Chemistry of Genus Allium and Brassica Plants
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    Chapter 14 Allium Vegetables and the Potential for Chemoprevention of Cancer
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    Chapter 15 The Attributes of Selenium-Enriched Garlic in Cancer Prevention
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    Chapter 16 Is There a Need to Change the American Diet?
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    Chapter 17 The National 5 a Day for Better Health Program
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    Chapter 18 Nutritional Implications of Dietary Phytochemicals
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    Chapter 19 Designer Foods
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    Chapter 20 Wheat Bran, Colon Cancer, and Breast Cancer
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    Chapter 21 Diet, Nutrition, and Cancer Prevention
Attention for Chapter 10: Antitumorigenic effects of limonene and perillyl alcohol against pancreatic and breast cancer.
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Chapter title
Antitumorigenic effects of limonene and perillyl alcohol against pancreatic and breast cancer.
Chapter number 10
Book title
Dietary Phytochemicals in Cancer Prevention and Treatment
Published in
Advances in experimental medicine and biology, January 1996
DOI 10.1007/978-1-4613-0399-2_10
Pubmed ID
Book ISBNs
978-1-4613-8034-4, 978-1-4613-0399-2
Authors

Crowell, P L, Siar Ayoubi, A, Burke, Y D, Crowell, Pamela L., Ayoubi, A. Siar, Burke, Yvette D., Pamela L. Crowell, A. Siar Ayoubi, Yvette D. Burke

Abstract

Perillyl alcohol is a natural product from cherries and other edible plants. Perillyl alcohol and d-limonene, a closely related dietary monoterpene, have chemotherapeutic activity against pancreatic, mammary, and prostatic tumors. In addition, perillyl alcohol, limonene, and other dietary monoterpenes have chemopreventive activity. Several mechanisms may account for the antitumorigenic effects of monoterpenes. For example, many monoterpenes inhibit the post-translational isoprenylation of cell growth-regulatory proteins such as Ras. Perillyl alcohol induces apoptosis without affecting the rate of DNA synthesis in both liver and pancreatic tumor cells. In addition, monoterpene-treated, regressing rat mammary tumors exhibit increased expression of transforming growth factor beta concomitant with tumor remodeling/redifferentiation to a more benign phenotype. Monoterpenes are effective, nontoxic dietary antitumor agents which act through a variety of mechanisms of action and hold promise as a novel class of antitumor drugs for human cancer.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 1 2%
Unknown 57 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 14%
Student > Bachelor 8 14%
Student > Master 8 14%
Other 5 9%
Student > Doctoral Student 3 5%
Other 11 19%
Unknown 15 26%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 21%
Pharmacology, Toxicology and Pharmaceutical Science 7 12%
Medicine and Dentistry 6 10%
Chemistry 5 9%
Immunology and Microbiology 2 3%
Other 9 16%
Unknown 17 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2021.
All research outputs
#18,143,395
of 23,308,124 outputs
Outputs from Advances in experimental medicine and biology
#3,139
of 4,990 outputs
Outputs of similar age
#77,655
of 80,155 outputs
Outputs of similar age from Advances in experimental medicine and biology
#18
of 23 outputs
Altmetric has tracked 23,308,124 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,990 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 80,155 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.