Chapter title |
Microfluidic Approach to Cell Microencapsulation
|
---|---|
Chapter number | 5 |
Book title |
Cell Microencapsulation
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-6364-5_5 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6362-1, 978-1-4939-6364-5
|
Authors |
Varna Sharma, Michael Hunckler, Melur K. Ramasubramanian, Emmanuel C. Opara, Kalyan C. Katuri Ph.D., Kalyan C. Katuri |
Editors |
Emmanuel C. Opara |
Abstract |
Bioartificial pancreas made of insulin-secreting islets cells holds great promise in the treatment of individuals with Type-1 diabetes. Successful islet cell microencapsulation in biopolymers is a key step for providing immunoisolation of transplanted islet cells. Because of the variability in the size and shape of pancreatic islets, one of the main obstacles in their microencapsulation is the inability to consistently control shape, size, and microstructure of the encapsulating biopolymer capsule. In this chapter, we provide a detailed description of a microfluidic approach to islet cell encapsulation in alginate that might address the microencapsulation challenges. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 2 | 14% |
Student > Ph. D. Student | 1 | 7% |
Unspecified | 1 | 7% |
Student > Bachelor | 1 | 7% |
Student > Master | 1 | 7% |
Other | 0 | 0% |
Unknown | 8 | 57% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 2 | 14% |
Unspecified | 1 | 7% |
Materials Science | 1 | 7% |
Medicine and Dentistry | 1 | 7% |
Engineering | 1 | 7% |
Other | 0 | 0% |
Unknown | 8 | 57% |