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Transient Receptor Potential Canonical Channels and Brain Diseases

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Attention for Chapter 9: TRPC Channels and Neuron Development, Plasticity, and Activities
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Chapter title
TRPC Channels and Neuron Development, Plasticity, and Activities
Chapter number 9
Book title
Transient Receptor Potential Canonical Channels and Brain Diseases
Published in
Advances in experimental medicine and biology, January 2017
DOI 10.1007/978-94-024-1088-4_9
Pubmed ID
Book ISBNs
978-9-40-241086-0, 978-9-40-241088-4, 978-9-40-241086-0, 978-9-40-241088-4
Authors

Yilin Tai, Yichang Jia, Tai, Yilin, Jia, Yichang

Abstract

In this chapter, we mainly focus on the functions of TRPC channels in brain development, including neural progenitor proliferation, neurogenesis, neuron survival, axon guidance, dendritic morphology, synaptogenesis, and neural plasticity. We also notice emerging advances in understanding the functions of TRPC channels in periphery, especially their functions in sensation and nociception in dorsal root ganglion (DRG). Because TRPC channels are expressed in all major types of glial cells, which account for at least half of total cells in the brain, TRPC channels may act as modulators for glial functions as well. The future challenges for studying these channels could be (1) the detailed protein structures of these channels, (2) their cell type-specific functions, (3) requirement for their specific blockers or activators, and (4) change in the channel conformation in the brain.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 6 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 33%
Student > Bachelor 2 33%
Researcher 1 17%
Student > Doctoral Student 1 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 67%
Agricultural and Biological Sciences 1 17%
Neuroscience 1 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 May 2017.
All research outputs
#15,459,013
of 22,971,207 outputs
Outputs from Advances in experimental medicine and biology
#2,512
of 4,957 outputs
Outputs of similar age
#257,209
of 421,094 outputs
Outputs of similar age from Advances in experimental medicine and biology
#235
of 490 outputs
Altmetric has tracked 22,971,207 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,957 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 421,094 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 490 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.