| Chapter title |
FtsZ-ring Architecture and Its Control by MinCD
|
|---|---|
| Chapter number | 7 |
| Book title |
Prokaryotic Cytoskeletons
|
| Published in |
Sub cellular biochemistry, May 2017
|
| DOI | 10.1007/978-3-319-53047-5_7 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-953045-1, 978-3-31-953047-5
|
| Authors |
Szwedziak, Piotr, Ghosal, Debnath, Piotr Szwedziak, Debnath Ghosal |
| Editors |
Jan Löwe, Linda A. Amos |
| Abstract |
In bacteria and archaea, the most widespread cell division system is based on the tubulin homologue FtsZ protein, whose filaments form the cytokinetic Z-ring. FtsZ filaments are tethered to the membrane by anchors such as FtsA and SepF and are regulated by accessory proteins. One such set of proteins is responsible for Z-ring's spatiotemporal regulation, essential for the production of two equal-sized daughter cells. Here, we describe how our still partial understanding of the FtsZ-based cell division process has been progressed by visualising near-atomic structures of Z-rings and complexes that control Z-ring positioning in cells, most notably the MinCDE and Noc systems that act by negatively regulating FtsZ filaments. We summarise available data and how they inform mechanistic models for the cell division process. |
X Demographics
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|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 25 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 20% |
| Researcher | 4 | 16% |
| Student > Ph. D. Student | 3 | 12% |
| Unspecified | 2 | 8% |
| Student > Doctoral Student | 1 | 4% |
| Other | 2 | 8% |
| Unknown | 8 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 9 | 36% |
| Unspecified | 2 | 8% |
| Agricultural and Biological Sciences | 2 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
| Immunology and Microbiology | 1 | 4% |
| Other | 2 | 8% |
| Unknown | 8 | 32% |