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X Demographics
Mendeley readers
Attention Score in Context
| Chapter title |
Affinity Depletion of Plasma and Serum for Mass Spectrometry-Based Proteome Analysis
|
|---|---|
| Chapter number | 1 |
| Book title |
Proteomics for Biomarker Discovery
|
| Published in |
Methods in molecular biology, March 2013
|
| DOI | 10.1007/978-1-62703-360-2_1 |
| Pubmed ID | |
| Book ISBNs |
978-1-62703-359-6, 978-1-62703-360-2
|
| Authors |
Julian A. J. Jaros, Paul C. Guest, Sabine Bahn, Daniel Martins-de-Souza, Jaros JA, Guest PC, Bahn S, Martins-de-Souza D, Jaros, Julian A. J., Guest, Paul C., Bahn, Sabine, Martins-de-Souza, Daniel |
| Abstract |
Protein biomarker discovery in blood plasma and serum is severely hampered by the vast dynamic range of the proteome. With protein concentrations spanning 12 orders of magnitude, conventional mass spectrometric analysis allows for detection of only a few low-abundance proteins. Prior depletion of high-abundant proteins from the sample can increase analytical depth considerably and has become a widely used practice. We describe in detail an affinity depletion method that selectively removes 14 of the most abundant proteins in plasma and serum. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 2 | 4% |
| United Kingdom | 1 | 2% |
| Unknown | 47 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 20% |
| Researcher | 10 | 20% |
| Student > Master | 8 | 16% |
| Student > Bachelor | 4 | 8% |
| Other | 2 | 4% |
| Other | 2 | 4% |
| Unknown | 14 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 9 | 18% |
| Agricultural and Biological Sciences | 9 | 18% |
| Medicine and Dentistry | 5 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 8% |
| Chemistry | 3 | 6% |
| Other | 6 | 12% |
| Unknown | 14 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2013.
All research outputs
#18,357,514
of 22,736,112 outputs
Outputs from Methods in molecular biology
#7,854
of 13,086 outputs
Outputs of similar age
#148,658
of 195,275 outputs
Outputs of similar age from Methods in molecular biology
#19
of 32 outputs
Altmetric has tracked 22,736,112 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,086 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,275 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.