| Chapter title |
Oxidized Low-Density Lipoprotein
|
|---|---|
| Chapter number | 24 |
| Book title |
Free Radicals and Antioxidant Protocols
|
| Published in |
Methods in molecular biology, November 2009
|
| DOI | 10.1007/978-1-60327-029-8_24 |
| Pubmed ID | |
| Book ISBNs |
978-1-58829-710-5, 978-1-60327-029-8
|
| Authors |
Sampath Parthasarathy, Achuthan Raghavamenon, Mahdi Omar Garelnabi, Nalini Santanam, Parthasarathy S, Raghavamenon A, Garelnabi MO, Santanam N, Parthasarathy, Sampath, Raghavamenon, Achuthan, Garelnabi, Mahdi Omar, Santanam, Nalini |
| Abstract |
Oxidized low-density lipoprotein (Ox-LDL) has been studied for over 25 years. Numerous pro- and anti-atherogenic properties have been attributed to Ox-LDL. Yet, Ox-LDL has neither been defined nor characterized, as its components and composition change depending on its source, method of preparation, storage, and use. It contains unoxidized and oxidized fatty acid derivatives both in the ester and free forms, their decomposition products, cholesterol and its oxidized products, proteins with oxidized amino acids and cross-links, and polypeptides with varying extents of covalent modification with lipid oxidation products, and many others. It seems to exist in vivo in some form not yet fully characterized. Until its pathophysiological significance, and how it is generated in vivo are determined, the nature of its true identity will be only of classical interest. In this review, its components, their biological actions and methods of preparation will be discussed. |
X Demographics
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| France | 2 | 10% |
| Nicaragua | 1 | 5% |
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| Unknown | 10 | 50% |
Demographic breakdown
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| Members of the public | 16 | 80% |
| Practitioners (doctors, other healthcare professionals) | 3 | 15% |
| Scientists | 1 | 5% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | <1% |
| Germany | 1 | <1% |
| Austria | 1 | <1% |
| United Kingdom | 1 | <1% |
| Brazil | 1 | <1% |
| Mauritius | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 339 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 75 | 22% |
| Student > Master | 48 | 14% |
| Student > Ph. D. Student | 47 | 14% |
| Researcher | 38 | 11% |
| Student > Postgraduate | 18 | 5% |
| Other | 46 | 13% |
| Unknown | 75 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 67 | 19% |
| Agricultural and Biological Sciences | 55 | 16% |
| Biochemistry, Genetics and Molecular Biology | 52 | 15% |
| Pharmacology, Toxicology and Pharmaceutical Science | 17 | 5% |
| Nursing and Health Professions | 14 | 4% |
| Other | 55 | 16% |
| Unknown | 87 | 25% |