Chapter title |
Tissue resources for clinical use and marker studies in melanoma.
|
---|---|
Chapter number | 37 |
Book title |
Molecular Diagnostics for Melanoma
|
Published in |
Methods in molecular biology, October 2013
|
DOI | 10.1007/978-1-62703-727-3_37 |
Pubmed ID | |
Book ISBNs |
978-1-62703-726-6, 978-1-62703-727-3
|
Authors |
Jonathan L Curry, Michael A Davies, Tiffany L Calderone, Katherine Nathanson, Victor G Prieto, Jeffrey E Gershenwald, Curry JL, Davies MA, Calderone TL, Nathanson K, Prieto VG, Gershenwald JE, Curry, Jonathan L., Davies, Michael A., Calderone, Tiffany L., Nathanson, Katherine, Prieto, Victor G., Gershenwald, Jeffrey E., Jonathan L. Curry, Michael A. Davies, Tiffany L. Calderone, Victor G. Prieto, Jeffrey E. Gershenwald |
Abstract |
The adequate procurement and preservation of high-quality tissue specimens from patients with melanoma is a critical clinical issue as patients' tumor samples are now used not only for pathological diagnosis but are also necessary to determine the molecular signature of the tumor to stratify patients who may benefit from targeted melanoma therapy. Tissue resources available for physicians and investigators include formalin-fixed paraffin-embedded (FFPE) tissue and frozen tissue, either preserved in optimal cutting temperature (OCT) media or snap frozen. Properly preserved tissue may be used to evaluate melanoma biomarkers by immunohistochemistry (IHC) with tissue microarray (TMA) technology, to perform genetic and genomic analyses, and for other types of translational research in melanoma. |
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Mendeley readers
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