Chapter title |
Generation of a Three-Dimensional Kidney Structure from Pluripotent Stem Cells
|
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Chapter number | 13 |
Book title |
Organ Regeneration
|
Published in |
Methods in molecular biology, March 2017
|
DOI | 10.1007/978-1-4939-6949-4_13 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6947-0, 978-1-4939-6949-4, 978-1-4939-6947-0, 978-1-4939-6949-4
|
Authors |
Yoshimura, Yasuhiro, Taguchi, Atsuhiro, Nishinakamura, Ryuichi, Yasuhiro Yoshimura, Atsuhiro Taguchi, Ryuichi Nishinakamura |
Editors |
Takashi Tsuji |
Abstract |
The kidney is a vital organ that has an important role in the maintenance of homeostasis by fluid volume regulation and waste product excretion. This role cannot be performed without the three-dimensional (3D) structure of the kidney. Therefore, it is important to generate the 3D structure of the kidney when inducing functional kidney tissue or the whole organ from pluripotent stem cells. In this chapter, we describe the detailed methods to induce kidney progenitor cells from pluripotent stem cells, which are based on embryological development. We also provide a method to generate 3D kidney tissue with vascularized glomeruli upon transplantation. |
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Researcher | 4 | 19% |
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Professor | 2 | 10% |
Professor > Associate Professor | 2 | 10% |
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Unknown | 1 | 5% |
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Medicine and Dentistry | 2 | 10% |
Nursing and Health Professions | 1 | 5% |
Other | 2 | 10% |
Unknown | 2 | 10% |