Chapter title |
Lead Exposure and Oxidative Stress: A Systematic Review
|
---|---|
Chapter number | 3 |
Book title |
Reviews of Environmental Contamination and Toxicology Volume 236
|
Published in |
Reviews of Environmental Contamination and Toxicology, January 2016
|
DOI | 10.1007/978-3-319-20013-2_3 |
Pubmed ID | |
Book ISBNs |
978-3-31-920012-5, 978-3-31-920013-2
|
Authors |
Ana Carolina B. Almeida Lopes, Tiago S. Peixe, Arthur E. Mesas, Monica M. B. Paoliello, Lopes, Ana Carolina B. Almeida, Peixe, Tiago S., Mesas, Arthur E., Paoliello, Monica M. B. |
Editors |
Pim de Voogt |
Abstract |
Lead is an environmental toxicant that can induce oxidative stress (OS) via reactive oxygen species (ROS) generation, which has been reported as an important mechanism underlying lead toxicity (Gurer and Ercal 2000; Pande and Flora 2002; Kasperczyk et al. 2004a; Farmand et al. 2005; Verstraeten et al. 2008; Wang et al. 2009; Martinez-Haro et al. 2011). OS occurs when the generation of ROS exceeds the antioxidant system's ability to defend cells against oxidized molecules. ROS is a term generally used to refer to free radicals derived from O2 (e.g., superoxide anions [O2 (-)] and hydroxyl radicals [OH(-)]) or to non-radical species (e.g. hydrogen peroxide [H2O2]) (Halliwell and Cross 1994). |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 1% |
Unknown | 99 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 19 | 19% |
Student > Master | 11 | 11% |
Researcher | 6 | 6% |
Student > Bachelor | 6 | 6% |
Unspecified | 5 | 5% |
Other | 18 | 18% |
Unknown | 35 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 9 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 8% |
Agricultural and Biological Sciences | 7 | 7% |
Medicine and Dentistry | 7 | 7% |
Unspecified | 6 | 6% |
Other | 21 | 21% |
Unknown | 42 | 42% |