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Targeted Therapy of Acute Myeloid Leukemia

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Cover of 'Targeted Therapy of Acute Myeloid Leukemia'

Table of Contents

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    Book Overview
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    Chapter 1 Genetics and Classification of Acute Myeloid Leukemia
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    Chapter 2 The Use of “Omics” to Guide the Selection of Targeted Therapy
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    Chapter 3 Roles of Apoptosis-Regulating Bcl-2 Family Genes in AML
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    Chapter 4 Bcl-2 Family: Translational Aspects
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    Chapter 5 IAP Family of Proteins as Therapeutic Targets for Acute Myeloid Leukemia
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    Chapter 6 TP53 Mutations in Acute Myeloid Leukemia
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    Chapter 7 Targeting p53 Tumor Suppressor for AML Therapy
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    Chapter 8 AML-Selective Apoptosis Induction by Rationally Designed Death Ligand Fusion Proteins
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    Chapter 9 PIM Kinases in AML
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    Chapter 10 Development of Midostaurin as a Tyrosine Kinase Inhibitor
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    Chapter 11 FLT3 in AML
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    Chapter 12 FLT3-ITD. Clinical (Sorafenib/AC220)
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    Chapter 13 Nucleophosmin (NPM1)
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    Chapter 14 Raf/MEK/ERK Signaling
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    Chapter 15 The Role of Translational Medicine in Optimization of Therapies Targeting the RAS-MAP Kinase Pathway
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    Chapter 16 Clinical Use of Farnesyltransferase Inhibitors
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    Chapter 17 The PI3K-AKT-mTOR Signaling Network in AML
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    Chapter 18 Targeting the PI3 Kinase-mTOR Signaling Pathway in AML
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    Chapter 19 Aurora Kinases
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    Chapter 20 The Clinical Development of Aurora Kinase Inhibitors in Acute Myeloid Leukemia
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    Chapter 21 AML: Deacetylases
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    Chapter 22 Methylation in AML: Clinical Applications
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    Chapter 23 PML/RARA as the Master Driver of APL Pathogenesis and Therapy Response
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    Chapter 24 Arsenic Trioxide in Untreated APL
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    Chapter 25 Targeting PML-RARα with Retinoids
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    Chapter 26 NR4A Orphan Receptors as Drug Targets
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    Chapter 27 Antibody-Based Therapeutics Targeting CD33, CD45, and CD66
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    Chapter 28 New Heterogeneity of the Leukemic Stem Cells
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    Chapter 29 Targeting Leukemia Stem Cells
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    Chapter 30 Regulation of Hematopoiesis by CXCL12/CXCR4 Signaling
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    Chapter 31 CXCR4/CXCL12 as a Therapeutic Target
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    Chapter 32 VLA-4: A Cell’s Consequential Encounter
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    Chapter 33 VLA-4 Function and Prognosis in Acute Myeloid Leukemia
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    Chapter 34 VLA4 in Acute Lymphoblastic Leukemia
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    Chapter 35 The Leukemic Bone Marrow Microenvironment: Targeting Hypoxia with Hypoxia-Activated Prodrugs
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    Chapter 36 MicroRNAs as Therapeutic Targets
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    Chapter 37 Clinical Implications of MicroRNAs in AML
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    Chapter 38 Inhibition of Glycolysis as a Therapeutic Strategy in Acute Myeloid Leukemias
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    Chapter 39 Molecular and Biochemical Basis for the Reprogramming of Intermediary Metabolism in Leukemia Cells
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    Chapter 40 NK-Cell Immunotherapy for AML
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    Chapter 41 Allogeneic and Autologous T cell Strategies to Enhance Targeting of Acute Myeloid Leukemias
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    Chapter 42 Indications for Hematopoietic Transplantation for AML
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    Chapter 43 Mesenchymal Stem/Stromal Cell-Targeted Therapies for Solid Tumors and Hematological Malignancies
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    Chapter 44 Erratum to: NK-Cell Immunotherapy for AML
Overall attention for this book and its chapters
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Citations

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Title
Targeted Therapy of Acute Myeloid Leukemia
Published by
Springer Nature, January 2015
DOI 10.1007/978-1-4939-1393-0
ISBNs
978-1-4939-1392-3, 978-1-4939-1393-0
Editors

Andreeff, Michael

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 1%
Czechia 1 1%
Unknown 71 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 22%
Researcher 13 18%
Student > Bachelor 10 14%
Student > Master 8 11%
Professor > Associate Professor 4 5%
Other 13 18%
Unknown 9 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 25%
Medicine and Dentistry 16 22%
Biochemistry, Genetics and Molecular Biology 10 14%
Chemistry 6 8%
Engineering 5 7%
Other 9 12%
Unknown 9 12%

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