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Mammalian Cell Cultures for Biologics Manufacturing

Overview of attention for book
Attention for Chapter 258: Lifecycle Management for Recombinant Protein Production Using Mammalian Cell Culture Technology.
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Chapter title
Lifecycle Management for Recombinant Protein Production Using Mammalian Cell Culture Technology.
Chapter number 258
Book title
Mammalian Cell Cultures for Biologics Manufacturing
Published in
Advances in biochemical engineering biotechnology, November 2013
DOI 10.1007/10_2013_258
Pubmed ID
Book ISBNs
978-3-64-254049-3, 978-3-64-254050-9
Authors

Moran E, Gammell P, Enda Moran, Patrick Gammell, Moran, Enda, Gammell, Patrick

Abstract

Product lifecycle management refers to the oversight process and activities carried out to fully realize the commercial potential and value of a product in the marketplace. It is typical for many changes to be introduced to the production processes and testing methods for biopharmaceutical drugs over their lifetime in the commercial marketplace. Technology lifecycle management, as discussed here, refers to the management of the different phases or generations of processes and methods used to make and test the active biopharmaceutical ingredient or drug product, and the adoption of different devices used to present the drug product to patients. The factors to consider when making changes to a commercial biopharmaceutical manufacturing process as part of a technology lifecycle management program are discussed. A case study outlines one approach taken in bringing forward a major process change to a cell culture process for the production of a therapeutic recombinant protein.

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 25%
Student > Ph. D. Student 3 25%
Student > Doctoral Student 1 8%
Student > Bachelor 1 8%
Lecturer > Senior Lecturer 1 8%
Other 3 25%
Readers by discipline Count As %
Engineering 4 33%
Agricultural and Biological Sciences 3 25%
Medicine and Dentistry 2 17%
Nursing and Health Professions 1 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 8%
Other 1 8%