You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Chapter title |
Microchannels for the Study of T Cell Immunological Synapses and Kinapses
|
---|---|
Chapter number | 20 |
Book title |
The Immune Synapse
|
Published in |
Methods in molecular biology, March 2017
|
DOI | 10.1007/978-1-4939-6881-7_20 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6879-4, 978-1-4939-6881-7
|
Authors |
Hélène D. Moreau, Philippe Bousso, Ana-Maria Lennon-Duménil |
Editors |
Cosima T. Baldari, Michael L. Dustin |
Abstract |
T Cells can form very stable (synapses) or very transient and migratory (kinapses) contacts with antigen-presenting cells. Here, we describe how microchannels can be used to conveniently study the distinct dynamics of T cells during antigen recognition. Microchannels provide a controlled confined environment that promotes T cell migration and recapitulates kinapse and synapse behaviors when coated with appropriate pMHC molecules. We also depict the advantages of this in vitro approach for addressing mechanistic issues and for analysis. |
Mendeley readers
The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 10 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 2 | 20% |
Researcher | 2 | 20% |
Student > Master | 2 | 20% |
Professor | 1 | 10% |
Unspecified | 1 | 10% |
Other | 1 | 10% |
Unknown | 1 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 2 | 20% |
Immunology and Microbiology | 2 | 20% |
Agricultural and Biological Sciences | 1 | 10% |
Unspecified | 1 | 10% |
Computer Science | 1 | 10% |
Other | 1 | 10% |
Unknown | 2 | 20% |