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The Funnel: From the Skull Base to the Sacrum

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Attention for Chapter: Comparison Between Ventricular and Spinal Infusion Tests in Suspected Normal Pressure Hydrocephalus.
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Chapter title
Comparison Between Ventricular and Spinal Infusion Tests in Suspected Normal Pressure Hydrocephalus.
Book title
The Funnel: From the Skull Base to the Sacrum
Published in
Acta neurochirurgica Supplement, December 2023
DOI 10.1007/978-3-031-36084-8_34
Pubmed ID
Book ISBNs
978-3-03-136083-1, 978-3-03-136084-8
Authors

Signorelli, Francesco, Trevisi, Gianluca, Visocchi, Massimiliano, Anile, Carmelo

Abstract

Idiopathic normal pressure hydrocephalus (iNPH) is an often-overlooked or misdiagnosed brain disorder characterized by overt ventriculomegaly and associated with gait disturbances, cognitive impairment, and urinary incontinence. If correctly diagnosed, it is considered the only form of dementia treatable with surgery, namely through a ventriculoperitoneal or ventriculoatrial shunt with programmable valves.Among the 856 spinal and ventricular infusion tests performed from 2001 to 2017 at our institution, we analyzed 106 cases selected for suspected normotensive hydrocephalus. In all cases, Intracranial Elastance Index (IEI) and outflow resistance (Rout) values were calculated: 52 of these patients underwent Spinal Katzman Test (SKT), and the remaining 54 underwent an intraventricular infusion test (IVKT). Of the 40 patients in the SKT group with pathological elastance (71%), 17 also had a Rout >12 mmHg and 23 a Rout <12 mmHg. Of the 50 patients in the IVKT group with pathological elastance (92%), 38 also had a Rout >12 mmHg and 12 a Rout <12 mmHg.IVKT and SKT to date represent two useful tools in the diagnosis of normal pressure hydrocephalus. Despite being more invasive, IVKT, including both the intracranial elastance index (IEI) and Rout analysis, could be considered more reliable than SKT and therefore could be reserved for the most controversial cases.

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Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 December 2023.
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#22,471,971
of 25,069,047 outputs
Outputs from Acta neurochirurgica Supplement
#151
of 200 outputs
Outputs of similar age
#399,790
of 472,541 outputs
Outputs of similar age from Acta neurochirurgica Supplement
#1
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