Ferroptosis
Springer US
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Attention Score in Context
| Chapter title |
Generation of Organoids and Analysis of Ferroptosis in Organoids.
|
|---|---|
| Book title |
Ferroptosis
|
| Published in |
Methods in molecular biology, January 2023
|
| DOI | 10.1007/978-1-0716-3433-2_11 |
| Pubmed ID | |
| Book ISBNs |
978-1-07-163432-5, 978-1-07-163433-2
|
| Authors |
Li, Wenxin, Su, Yujie, Guo, Jingyi, Wang, Mengfei, Liu, Xingguo |
| Abstract |
Ferroptosis is a unique form of iron-dependent cell death induced by lipid peroxidation and subsequent plasma membrane rupture, which sets it apart from other types of regulated cell death. Ferroptosis has been linked to a diverse range of biological processes, such as aging, immunity, and cancer. Organoids, on the other hand, are three-dimensional (3D) miniaturized model systems of different organs in vitro cultures, which have gained widespread interest for modeling tissue development and disease, drug screening, and cell therapy. Organoids offer tremendous potential for improving our understanding of human diseases, particularly in the search for the field of ferroptosis in pathological processes of organs. Furthermore, cancer organoids are utilized to investigate molecular mechanisms and drug screening in vitro due to the anti-tumor effect of ferroptosis. Currently, the development of liver organoids has reached a relatively mature stage. Here, we present the protocols for the generation of liver organoids and liver cancer organoids, along with the methods for detecting ferroptosis in organoids. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2023.
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#16,490,096
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Outputs from Methods in molecular biology
#5,711
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Outputs of similar age
#249,976
of 446,430 outputs
Outputs of similar age from Methods in molecular biology
#261
of 656 outputs
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