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Advances in Nutrition and Cancer 2

Overview of attention for book
Cover of 'Advances in Nutrition and Cancer 2'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Diet and Cancer
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    Chapter 2 EPIC-Italy
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    Chapter 3 Nutritional factors in human cancers.
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    Chapter 4 Alcohol and Cancer
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    Chapter 5 Energy Sources and Risk of Cancer of the Breast and Colon-Rectum in Italy
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    Chapter 6 Organochlorines and Breast Cancer
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    Chapter 7 Olive Oil Consumption and Cancer Mortality in Italy
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    Chapter 8 Cell Division Cycle Alterations and Human Tumors
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    Chapter 9 Regulation of p53 Function in Normal and Malignant Cells
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    Chapter 10 The Role of Micronutrients in DNA Synthesis and Maintenance
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    Chapter 11 Biological Effects of Hydroxytyrosol, a Polyphenol from Olive Oil Endowed with Antioxidant Activity
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    Chapter 12 Protective Effects of Butyric Acid in Colon Cancer
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    Chapter 13 Short-Chain Fatty Acid in the Human Colon
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    Chapter 14 Brassica vegetables and cancer prevention. Epidemiology and mechanisms.
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    Chapter 15 Stilbenes and Bibenzyls with Potential Anticancer or Chemopreventive Activity
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    Chapter 16 Post-Translational Modifications of Eukaryotic Initiation Factor-5A (eIF-5a) as a New Target for Anti-Cancer Therapy
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    Chapter 17 Diet, Fibers, and Colon Cancer
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    Chapter 18 Phytochemicals as Modulators of Cancer Risk
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    Chapter 19 Low Dose Exposure to Carcinogens and Metabolic Gene Polymorphisms
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    Chapter 20 Carcinogen-DNA Adducts as Tools in Risk Assessment
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    Chapter 21 Significance of Genetic Polymorphisms in Cancer Susceptibility
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    Chapter 22 DNA Repair Pathways and Cancer Prevention
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    Chapter 23 Cereals, Fiber, and Cancer Prevention
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    Chapter 24 Carnitine System and Tumor
Attention for Chapter 14: Brassica vegetables and cancer prevention. Epidemiology and mechanisms.
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

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9 news outlets
blogs
1 blog
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3 X users
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3 Facebook pages

Citations

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11 Dimensions

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34 Mendeley
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Chapter title
Brassica vegetables and cancer prevention. Epidemiology and mechanisms.
Chapter number 14
Book title
Advances in Nutrition and Cancer 2
Published in
Advances in experimental medicine and biology, January 1999
DOI 10.1007/978-1-4757-3230-6_14
Pubmed ID
Book ISBNs
978-1-4419-3331-7, 978-1-4757-3230-6
Authors

van Poppel, G, Verhoeven, D T, Verhagen, H, Goldbohm, R A, Geert van Poppel, Dorette T. H. Verhoeven, Hans Verhagen, R. Alexandra Goldbohm, Poppel, Geert, Verhoeven, Dorette T. H., Verhagen, Hans, Goldbohm, R. Alexandra

Editors

Vincenzo Zappia, Fulvio Della Ragione, Alfonso Barbarisi, Gian Luigi Russo, Rossano Dello Iacovo

Abstract

This paper first gives an overview of the epidemiological data concerning the cancer-preventive effect of brassica vegetables, including cabbages, kale, broccoli, Brussels sprouts, and cauliflower. A protective effect of brassicas against cancer may be plausible due to their relatively high content of glucosinolates. Certain hydrolysis products of glucosinolates have shown anticarcinogenic properties. The results of six cohort studies and 74 case-control studies on the association between brassica consumption and cancer risk are summarized. The cohort studies showed inverse associations between the consumption of brassica's and risk of lung cancer, stomach cancer, all cancers taken together. Of the case-control studies 64% showed an inverse association between consumption of one or more brassica vegetables and risk of cancer at various sites. Although the measured effects might have been distorted by various types of bias, it is concluded that a high consumption of brassica vegetables is associated with a decreased risk of cancer. This association appears to be most consistent for lung, stomach, colon and rectal cancer, and least consistent for prostatic, endometrial and ovarian cancer. It is not yet possible to resolve whether associations are to be attributed to brassica vegetables per se or to vegetables in general. Further epidemiological research should separate the anticarcinogenic effect of brassica vegetables from the effect of vegetables in general. The mechanisms by which brassica vegetables might decrease the risk of cancer are reviewed in the second part of this paper. Brassicas, including all types of cabbages, broccoli, cauliflower, and Brussels sprouts, may be protective against cancer due to their glucosinolate content. Glucosinolates are usually broken down through hydrolysis catalysed by myrosinase, an enzyme that is released from damaged plant cells. Some of the hydrolysis products, viz. indoles, and isothiocyanates, are able to influence phase 1 and phase 2 biotransformation enzyme activities, thereby possibly influencing several processes related to chemical carcinogenesis, e.g. the metabolism, DNA-binding, and mutagenic activity of promutagens. Most evidence concerning anticarcinogenic effects of glucosinolate hydrolysis products and brassica vegetables has come from studies in animals. In addition, studies carried out in humans using high but still realistic human consumption levels of indoles and brassica vegetables have shown putative positive effects on health. The combination of epidemiological and experimental data provide suggestive evidence for a cancer preventive effect of a high intake of brassica vegetables.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 18%
Researcher 6 18%
Student > Master 5 15%
Student > Bachelor 4 12%
Student > Doctoral Student 2 6%
Other 6 18%
Unknown 5 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 32%
Medicine and Dentistry 5 15%
Biochemistry, Genetics and Molecular Biology 4 12%
Chemistry 3 9%
Engineering 2 6%
Other 3 9%
Unknown 6 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 83. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2021.
All research outputs
#505,136
of 25,144,989 outputs
Outputs from Advances in experimental medicine and biology
#60
of 5,272 outputs
Outputs of similar age
#358
of 103,552 outputs
Outputs of similar age from Advances in experimental medicine and biology
#3
of 47 outputs
Altmetric has tracked 25,144,989 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,272 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 103,552 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.