| Chapter title |
Microbial Rhodopsins
|
|---|---|
| Chapter number | 1 |
| Book title |
Rhodopsin
|
| Published in |
Methods in molecular biology, January 2022
|
| DOI | 10.1007/978-1-0716-2329-9_1 |
| Pubmed ID | |
| Book ISBNs |
978-1-07-162328-2, 978-1-07-162329-9
|
| Authors |
Gordeliy, Valentin, Kovalev, Kirill, Bamberg, Ernst, Rodriguez-Valera, Francisco, Zinovev, Egor, Zabelskii, Dmitrii, Alekseev, Alexey, Rosselli, Riccardo, Gushchin, Ivan, Okhrimenko, Ivan |
| Abstract |
The first microbial rhodopsin, a light-driven proton pump bacteriorhodopsin from Halobacterium salinarum (HsBR), was discovered in 1971. Since then, this seven-α-helical protein, comprising a retinal molecule as a cofactor, became a major driver of groundbreaking developments in membrane protein research. However, until 1999 only a few archaeal rhodopsins, acting as light-driven proton and chloride pumps and also photosensors, were known. A new microbial rhodopsin era started in 2000 when the first bacterial rhodopsin, a proton pump, was discovered. Later it became clear that there are unexpectedly many rhodopsins, and they are present in all the domains of life and even in viruses. It turned out that they execute such a diversity of functions while being "nearly the same." The incredible evolution of the research area of rhodopsins and the scientific and technological potential of the proteins is described in the review with a focus on their function-structure relationships. |
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|---|---|---|
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| Argentina | 1 | 17% |
| Israel | 1 | 17% |
| United States | 1 | 17% |
| Unknown | 2 | 33% |
Demographic breakdown
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|---|---|---|
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| Scientists | 1 | 17% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 30 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 40% |
| Student > Master | 3 | 10% |
| Student > Bachelor | 3 | 10% |
| Unspecified | 1 | 3% |
| Other | 1 | 3% |
| Other | 2 | 7% |
| Unknown | 8 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 11 | 37% |
| Agricultural and Biological Sciences | 6 | 20% |
| Chemistry | 2 | 7% |
| Unspecified | 1 | 3% |
| Neuroscience | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 8 | 27% |