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Dendritic Cells

Overview of attention for book
Cover of 'Dendritic Cells'

Table of Contents

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    Book Overview
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    Chapter 1 Origin, Phenotype, and Function of Mouse Dendritic Cell Subsets.
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    Chapter 2 Phenotypes and Functions of Human Dendritic Cell Subsets in the Tumor Microenvironment.
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    Chapter 3 In Vivo Tracking of Dendritic Cell Migration
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    Chapter 4 In Vivo Analysis of Dendritic Cell Clonality.
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    Chapter 5 Monitoring the Interaction Between Dendritic Cells and T Cells In Vivo with LIPSTIC.
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    Chapter 6 In Vitro Generation of Murine Bone Marrow-Derived Dendritic Cells.
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    Chapter 7 In Vitro Generation of Murine Dendritic Cells from Hoxb8-Immortalized Hematopoietic Progenitors.
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    Chapter 8 In Vitro Generation of Murine CD8α + DEC205 + XCR1 + Cross-Presenting Dendritic Cells from Bone Marrow–Derived Hematopoietic Progenitors
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    Chapter 9 In Vitro Generation of Human Dendritic Cell Subsets from CD34+ Cord Blood Progenitors.
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    Chapter 10 In Vitro Generation of Human Cross-Presenting Type 1 Conventional Dendritic Cells (cDC1s) and Plasmacytoid Dendritic Cells (pDCs)
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    Chapter 11 Culture System Allowing the Simultaneous Differentiation of Human Monocytes into Dendritic Cells and Macrophages Using M-CSF, IL-4, and TNF-α
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    Chapter 12 Clonal Analysis of Human Dendritic Cell Progenitors Using a Stromal Cell Culture
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    Chapter 13 Enrichment of Large Numbers of Splenic Mouse Dendritic Cells After Injection of Flt3L-Producing Tumor Cells
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    Chapter 14 Isolation and Identification of Dendritic Cell Subsets from Human and Mouse Tumors
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    Chapter 15 Optimized Nonviral Gene Disruption in Primary Murine and Human Myeloid Cells
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    Chapter 16 Characterization of Dendritic Cell Metabolism by Flow Cytometry
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    Chapter 17 In Vivo and In Vitro Assay to Address Dendritic Cell Antigen Cross-Presenting Capacity
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    Chapter 18 Assays to Detect Cross-Dressing by Dendritic Cells In Vivo and In Vitro
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    Chapter 19 Assessing the Ability of Human Dendritic Cells to Stimulate Naive CD4 + and CD8 + T Cells
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    Chapter 20 In Vitro and In Vivo Assays to Evaluate Dendritic Cell Phagocytic Capacity
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    Chapter 21 Tracking Plasmacytoid Dendritic Cell Response to Physical Contact with Infected Cells.
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    Chapter 22 Harnessing Single-Cell RNA Sequencing to Identify Dendritic Cell Types, Characterize Their Biological States, and Infer Their Activation Trajectory.
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    Chapter 23 Characterization of Developmental Trajectories of Dendritic Cell Hematopoiesis Through Single-Cell RNA Sequencing Methods.
Attention for Chapter 2: Phenotypes and Functions of Human Dendritic Cell Subsets in the Tumor Microenvironment.
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Chapter title
Phenotypes and Functions of Human Dendritic Cell Subsets in the Tumor Microenvironment.
Chapter number 2
Book title
Dendritic Cells
Published in
Methods in molecular biology, January 2023
DOI 10.1007/978-1-0716-2938-3_2
Pubmed ID
Book ISBNs
978-1-07-162937-6, 978-1-07-162938-3
Authors

Sakref, Candice, Bendriss-Vermare, Nathalie, Valladeau-Guilemond, Jenny

Abstract

Dendritic cells (DCs) play a key role in the antitumor immunity, as they are at the interface of innate and adaptive immunity. This important task can only be performed thanks to the broad range of mechanisms that DCs can perform to activate other immune cells. As DCs are well known for their outstanding capacity to prime and activate T cells through antigen presentation, DCs were intensively investigated during the past decades. Numerous studies have identified new DC subsets, leading to a large variety of subsets commonly separated into cDC1, cDC2, pDCs, mature DCs, Langerhans cells, monocyte-derived DCs, Axl-DCs, and several other subsets. Here, we review the specific phenotypes, functions, and localization within the tumor microenvironment (TME) of human DC subsets thanks to flow cytometry and immunofluorescence but also with the help of high-output technologies such as single-cell RNA sequencing and imaging mass cytometry (IMC).

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 4 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 25%
Student > Doctoral Student 1 25%
Unknown 2 50%
Readers by discipline Count As %
Unspecified 1 25%
Immunology and Microbiology 1 25%
Unknown 2 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 March 2023.
All research outputs
#16,114,790
of 25,468,708 outputs
Outputs from Methods in molecular biology
#4,784
of 14,207 outputs
Outputs of similar age
#232,924
of 476,418 outputs
Outputs of similar age from Methods in molecular biology
#189
of 715 outputs
Altmetric has tracked 25,468,708 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,207 research outputs from this source. They receive a mean Attention Score of 3.5. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 476,418 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 715 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.