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HDAC/HAT Function Assessment and Inhibitor Development

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Cover of 'HDAC/HAT Function Assessment and Inhibitor Development'

Table of Contents

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    Book Overview
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    Chapter 1 Analyzing Lymphoma Development and Progression Using HDACi in Mouse Models
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    Chapter 2 Colony Formation Assay to Test the Impact of HDACi on Leukemic Cells
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    Chapter 3 Defined Human Leukemic CD34+ Liquid Cultures to Study HDAC/Transcriptional Repressor Complexes
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    Chapter 4 Development of a Cellular Model Mimicking Specific HDAC Inhibitors
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    Chapter 5 Evaluation of Antitumor and On-Target Activity of HDAC Inhibitors with the Zebrafish Embryo Xenograft Model
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    Chapter 6 Human Platelet Lysate as Valid Cell Growth Additive to Assess Protein Acetylation
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    Chapter 7 Investigating Physiopathological Roles for Sirtuins in a Mouse Model
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    Chapter 8 Patient-Derived Organoids for In Vivo Validation of In Vitro Data
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    Chapter 9 Analysis of HDACi-Coupled Nanoparticles: Opportunities and Challenges
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    Chapter 10 Development of Pyrazine-Anilinobenzamides as Histone Deacetylase HDAC1–3 Selective Inhibitors and Biological Testing Against Pancreas Cancer Cell Lines
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    Chapter 11 Evaluation of Small-Molecule HDAC Inhibitors Through In Vitro and In Cellulo Approaches
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    Chapter 12 Synthesis, Biochemical, and Cellular Evaluation of HDAC6 Targeting Proteolysis Targeting Chimeras
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    Chapter 13 HDACi Delivery Systems Based on Cellulose Valproate Nanoparticles
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    Chapter 14 Synthesis and Characterization of Reversible Covalent HDAC4 Inhibitors
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    Chapter 15 Analysis of Cell Cycle and DNA Compaction Dependent Subnuclear Distribution of Histone Marks
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    Chapter 16 Analyzing the Effects of HDAC Inhibitors on DNA Damage and Associated Cytotoxicity in Primary Hepatocytes
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    Chapter 17 Assessment of HDAC Inhibitor-Induced Endoplasmic Reticulum (ER) Stress
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    Chapter 18 Assessment of Mitochondrial Dysfunctions After Sirtuin Inhibition
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    Chapter 19 Assessing the Effect of Histone Deacetylase Inhibitors on DNA Double-Strand Break Repair by Nonhomologous End Joining
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    Chapter 20 Assessing SIRT7 Activity In Vivo and In Vitro in Response to DNA Damage
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    Chapter 21 Methods to Evaluate the Effects of HAT/KAT Inhibition on SIAH2-Driven Reactive Oxygen Species Generation in Helicobacter pylori-Infected Gastric Epithelial Cells
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    Chapter 22 Monitoring Changes in Intracellular Reactive Oxygen Species Levels in Response to Histone Deacetylase Inhibitors
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    Chapter 23 Single-Cell Analysis of Histone Acetylation Dynamics at Replication Forks Using PLA and SIRF
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    Chapter 24 Testing the Effect of Histone Acetyltransferases on Local Chromatin Compaction
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    Chapter 25 A Genome-Wide CRISPR-Cas9 Loss-of-Function Screening to Identify Host Restriction Factors Modulating Oncolytic Virotherapy
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    Chapter 26 Cloning Strategy for HDAC1/HDAC2 Hybrid Protein Expression in Mammalian Cells
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    Chapter 27 Continuous Histone Deacylase Activity Assays
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    Chapter 28 CRISPR Activation/Interference Screen to Identify Genetic Networks in HDAC-Inhibitor-Resistant Cells
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    Chapter 29 Determining Potency of Inhibitors Targeting Histone Deacetylase 6 by Quantification of Acetylated Tubulin in Cells
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    Chapter 30 Expression and Crystallization of HDAC6 Tandem Catalytic Domains
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    Chapter 31 Fluorescence Polarization-Based Competition Assays to Evaluate Histone Deacetylase 6 Inhibitors
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    Chapter 32 Immunoprecipitation of HDAC6 and Interacting Proteins
Attention for Chapter 23: Single-Cell Analysis of Histone Acetylation Dynamics at Replication Forks Using PLA and SIRF
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Chapter title
Single-Cell Analysis of Histone Acetylation Dynamics at Replication Forks Using PLA and SIRF
Chapter number 23
Book title
HDAC/HAT Function Assessment and Inhibitor Development
Published by
Humana, New York, NY, October 2022
DOI 10.1007/978-1-0716-2788-4_23
Pubmed ID
36255636
Book ISBNs
978-1-07-162787-7, 978-1-07-162788-4
Authors

Lee, Seo Yun, Kim, Jae Jin, Miller, Kyle M.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 2 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 2 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 1 50%
Unknown 1 50%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 50%
Unknown 1 50%

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