Orlikova B, Legrand N, Panning J, Dicato M, Diederich M, Barbora Orlikova, Noémie Legrand, Jana Panning, Mario Dicato, Marc Diederich, Orlikova, Barbora, Legrand, Noémie, Panning, Jana, Dicato, Mario, Diederich, Marc
Editors
Vincenzo Zappia, Salvatore Panico, Gian Luigi Russo, Alfredo Budillon, Fulvio Della Ragione
Abstract
Over the centuries, plant extracts have been used to treat various diseases. Until now, natural products have played an important role in anticancer therapy as there are more than 500 compounds from terrestrial and marine plants or microorganisms, which have antioxidant, antiproliferative, or antiangiogenic properties and are therefore able to reduce tumor growth. The recent discovery of new natural products has been accelerated by novel technologies (high throughput screening of natural products in plants, animals, marine organisms, and microorganisms). Vincristine, irinotecan, etoposide, and paclitaxel are examples of compounds derived from plants that are used in cancer treatment. Similarly, actinomycin D, mitomycin C, bleomycin, doxorubicin, and L-asparaginase are drugs derived from microorganisms. In this review, we describe the molecular mechanisms of natural compounds with anti-inflammatory and anticancer activities.
Pharmacology, Toxicology and Pharmaceutical Science
8
9%
Medicine and Dentistry
7
8%
Other
10
11%
Unknown
30
33%
Attention Score in Context
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 May 2016.
All research outputs
#5,439,840
of 22,757,090 outputs
Outputs from Cancer treatment and research
#31
of 165 outputs
Outputs of similar age
#48,545
of 210,334 outputs
Outputs of similar age from Cancer treatment and research
#10
of 17 outputs
Altmetric has tracked 22,757,090 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 165 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,334 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
