Brown Adipose Tissue
Springer US
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Attention Score in Context
| Chapter title |
Activating Human Adipose Tissue with the β3-Adrenergic Agonist Mirabegron.
|
|---|---|
| Book title |
Brown Adipose Tissue
|
| Published in |
Methods in molecular biology, January 2022
|
| DOI | 10.1007/978-1-0716-2087-8_5 |
| Pubmed ID | |
| Book ISBNs |
978-1-07-162086-1, 978-1-07-162087-8
|
| Authors |
Chen, Kong Y, Brychta, Robert J, Israni, Nikita S, Jiang, Alex, Lea, Hannah J, Lentz, Taylor N, Pierce, Anne E, Cypess, Aaron M, Chen, Kong Y., Brychta, Robert J., Israni, Nikita S., Lea, Hannah J., Lentz, Taylor N., Pierce, Anne E., Cypess, Aaron M., Kong Y. Chen, Robert J. Brychta, Nikita S. Israni, Alex Jiang, Hannah J. Lea, Taylor N. Lentz, Anne E. Pierce, Aaron M. Cypess |
| Abstract |
An appealing strategy for treatment of metabolic disease in humans is activation of brown adipose tissue (BAT), a thermogenic organ best visualized through 18F-FDG PET/CT. BAT has been activated to varying degrees by mild cold exposure. However, this approach can cause undesirable stress, and there remains no consensus protocol. Here, we describe standardized methods for both acute and chronic activation of BAT using the orally administered β3-adrenergic receptor (AR) agonist, mirabegron. Acute pharmacological stimulation has enabled quantification of whole-body BAT volume and metabolic activity using PET/CT imaging, and chronic stimulation increases these properties of BAT over time. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 8 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 63% |
| Student > Master | 1 | 13% |
| Unknown | 2 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 2 | 25% |
| Medicine and Dentistry | 2 | 25% |
| Sports and Recreations | 1 | 13% |
| Unknown | 3 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2022.
All research outputs
#18,789,320
of 23,283,373 outputs
Outputs from Methods in molecular biology
#8,087
of 13,326 outputs
Outputs of similar age
#364,385
of 507,520 outputs
Outputs of similar age from Methods in molecular biology
#331
of 596 outputs
Altmetric has tracked 23,283,373 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,326 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
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We're also able to compare this research output to 596 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.