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The Benefits of Natural Products for Neurodegenerative Diseases

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Cover of 'The Benefits of Natural Products for Neurodegenerative Diseases'

Table of Contents

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    Book Overview
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    Chapter 1 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 2 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 3 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 4 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 5 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 6 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 7 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 8 Impact of Non-Enzymatic Glycation in Neurodegenerative Diseases: Role of Natural Products in Prevention.
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    Chapter 9 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 10 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 11 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 12 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 13 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 14 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 15 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 16 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 17 Indian Herbs for the Treatment of Neurodegenerative Disease.
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    Chapter 18 Avocado as a Major Dietary Source of Antioxidants and Its Preventive Role in Neurodegenerative Diseases.
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    Chapter 19 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 20 Role of Polyunsaturated Fatty Acids and Their Metabolites on Stem Cell Proliferation and Differentiation.
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    Chapter 21 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 22 Modulatory Effects of Dietary Amino Acids on Neurodegenerative Diseases.
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    Chapter 23 Plant-Derived Natural Products for Parkinson's Disease Therapy.
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    Chapter 24 Erratum
Attention for Chapter 8: Impact of Non-Enzymatic Glycation in Neurodegenerative Diseases: Role of Natural Products in Prevention.
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Chapter title
Impact of Non-Enzymatic Glycation in Neurodegenerative Diseases: Role of Natural Products in Prevention.
Chapter number 8
Book title
The Benefits of Natural Products for Neurodegenerative Diseases
Published in
Advances in neurobiology, September 2016
DOI 10.1007/978-3-319-28383-8_8
Pubmed ID
Book ISBNs
978-3-31-928381-4, 978-3-31-928383-8
Authors

Saheem Ahmad, Mohammed Farhan, Ahmad, Saheem, Farhan, Mohammed

Editors

M. Mohamed Essa, Mohammed Akbar, Gilles Guillemin

Abstract

Non-enzymatic protein glycosylation is the addition of free carbonyls to the free amino groups of proteins, amino acids, lipoproteins and nucleic acids resulting in the formation of early glycation products. The early glycation products are also known as Maillard reaction which undergoes dehydration, cyclization and rearrangement to form advanced glycation end-products (AGEs). By and large the researchers in the past have also established that glycation and the AGEs are responsible for most type of metabolic disorders, including diabetes mellitus, cancer, neurological disorders and aging. The amassing of AGEs in the tissues of neurodegenerative diseases shows its involvement in diseases. Therefore, it is likely that inhibition of glycation reaction may extend the lifespan of an individual. The hunt for inhibitors of glycation, mainly using in vitro models, has identified natural compounds able to prevent glycation, especially polyphenols and other natural antioxidants. Extrapolation of results of in vitro studies on the in vivo situation is not straightforward due to differences in the conditions and mechanism of glycation, and bioavailability problems. Nevertheless, existing data allow postulating that enrichment of diet in natural anti-glycating agents may attenuate glycation and, in consequence may halt the aging and neurological problems.

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Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 35%
Researcher 2 12%
Student > Master 2 12%
Student > Doctoral Student 1 6%
Professor 1 6%
Other 4 24%
Unknown 1 6%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 18%
Agricultural and Biological Sciences 3 18%
Medicine and Dentistry 3 18%
Nursing and Health Professions 2 12%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Other 2 12%
Unknown 3 18%