| Chapter title |
The Benefits of Natural Products for Neurodegenerative Diseases
|
|---|---|
| Chapter number | 5 |
| Book title |
The Benefits of Natural Products for Neurodegenerative Diseases
|
| Published in |
Advances in neurobiology, September 2016
|
| DOI | 10.1007/978-3-319-28383-8_5 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-928381-4, 978-3-31-928383-8
|
| Authors |
Hussain, Farhan, Mittal, Sandeep, Joshee, Nirmal, Parajuli, Prahlad, Farhan Hussain, Sandeep Mittal, Nirmal Joshee, Prahlad Parajuli Ph.D., Prahlad Parajuli |
| Editors |
M. Mohamed Essa, Mohammed Akbar, Gilles Guillemin |
| Abstract |
Inflammation of the brain is one of the most highly researched yet mysterious areas in modern day neurology. The process of inflammation is a normal mechanism of wound healing that can result from acute injuries such as traumas or can be caused by genetic/environmental factors. After the initial insult, the immune system defenses, specifically microglial cells, are activated in order to combat the infection or injury. However, prolonged or chronic inflammation is often deleterious due mainly to accumulation of free reactive oxygen species (ROS) and other pro-inflammatory cytokines in the brain FADDIN EN.CITE. Plant-derived natural compounds have the potential to ameliorate the causes and symptoms of neuroinflammation, due to their various anti-oxidant and anti-inflammatory activities, without completely muting the immune defenses. Scutellaria is a perennial plant in the mint family that has been used to treat diseases in Asia and Eastern Europe throughout history. This chapter reviews the active components of various Scutellaria species and their mechanisms of action to prevent chronic neurologic disorders involving neuroinflammation and neurodegeneration. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 10% |
| Unknown | 9 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 3 | 30% |
| Researcher | 2 | 20% |
| Other | 1 | 10% |
| Professor | 1 | 10% |
| Student > Doctoral Student | 1 | 10% |
| Other | 2 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 2 | 20% |
| Medicine and Dentistry | 2 | 20% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 10% |
| Business, Management and Accounting | 1 | 10% |
| Agricultural and Biological Sciences | 1 | 10% |
| Other | 3 | 30% |