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The Benefits of Natural Products for Neurodegenerative Diseases

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Cover of 'The Benefits of Natural Products for Neurodegenerative Diseases'

Table of Contents

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    Book Overview
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    Chapter 1 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 2 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 3 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 4 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 5 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 6 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 7 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 8 Impact of Non-Enzymatic Glycation in Neurodegenerative Diseases: Role of Natural Products in Prevention.
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    Chapter 9 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 10 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 11 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 12 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 13 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 14 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 15 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 16 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 17 Indian Herbs for the Treatment of Neurodegenerative Disease.
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    Chapter 18 Avocado as a Major Dietary Source of Antioxidants and Its Preventive Role in Neurodegenerative Diseases.
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    Chapter 19 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 20 Role of Polyunsaturated Fatty Acids and Their Metabolites on Stem Cell Proliferation and Differentiation.
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    Chapter 21 The Benefits of Natural Products for Neurodegenerative Diseases
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    Chapter 22 Modulatory Effects of Dietary Amino Acids on Neurodegenerative Diseases.
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    Chapter 23 Plant-Derived Natural Products for Parkinson's Disease Therapy.
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    Chapter 24 Erratum
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Chapter title
The Benefits of Natural Products for Neurodegenerative Diseases
Chapter number 1
Book title
The Benefits of Natural Products for Neurodegenerative Diseases
Published in
Advances in neurobiology, September 2016
DOI 10.1007/978-3-319-28383-8_1
Pubmed ID
Book ISBNs
978-3-31-928381-4, 978-3-31-928383-8
Authors

Gangisetty, Omkaram, Murugan, Sengottuvelan, Omkaram Gangisetty, Sengottuvelan Murugan

Editors

M. Mohamed Essa, Mohammed Akbar, Gilles Guillemin

Abstract

Epigenetic modifications, including DNA methylation, covalent histone modifications, and small noncoding RNAs, play a key role in regulating the gene expression. This regulatory mechanism is important in cellular differentiation and development. Recent advances in the field of epigenetics extended the role of epigenetic mechanisms in controlling key biological processes such as genome imprinting and X-chromosome inactivation. Aberrant epigenetic modifications are associated with the development of many diseases. The role of epigenetic modifications in various neurodegenerative disorders including Alzheimer's disease, Parkinson's disease, Huntington disease, epilepsy, and multiple sclerosis is rapidly emerging. The use of epigenetic modifying drugs to treat these diseases has been the interest in recent years. A number of natural products having diverse mechanism of action are used for drug discovery. For many years, natural compounds have been used to treat various neurodegenerative diseases, but the use of such compounds as epigenetic modulators to reverse or treat neurological diseases are not well studied. In this chapter, we mainly focus on how various epigenetic modifications play a key role in neurodegenerative diseases, their mechanism of action, and how it acts as a potential therapeutic target for epigenetic drugs to treat these diseases will be discussed.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 19%
Student > Master 6 19%
Researcher 5 16%
Professor 3 9%
Student > Ph. D. Student 2 6%
Other 5 16%
Unknown 5 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 22%
Pharmacology, Toxicology and Pharmaceutical Science 5 16%
Neuroscience 4 13%
Medicine and Dentistry 3 9%
Nursing and Health Professions 2 6%
Other 4 13%
Unknown 7 22%