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Mendeley readers
Attention Score in Context
Chapter title |
Preparation of a naïve library of camelid single domain antibodies.
|
---|---|
Chapter number | 5 |
Book title |
Single Domain Antibodies
|
Published in |
Methods in molecular biology, August 2012
|
DOI | 10.1007/978-1-61779-968-6_5 |
Pubmed ID | |
Book ISBNs |
978-1-61779-967-9, 978-1-61779-968-6
|
Authors |
Olichon A, de Marco A, Aurelien Olichon, Ario de Marco |
Abstract |
The preparation of antibody libraries starting from lymphocytes recovered from immunized members of the Camelidae enables to collect binders that underwent somatic maturation. However, the time and costs necessary to prepare a library for each new antigen may urge to look for alternatives such as those offered by large one-pot libraries. Here we describe how to obtain a suitable naïve library using material from nonimmunized llamas. Despite the lack of somatic maturation, the selection based on phage display allowed to isolate from such naïve libraries VHHs with affinity in the subnanomolar range and suitable for the standard immunoapplications. |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Unknown | 55 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 25% |
Student > Ph. D. Student | 9 | 16% |
Student > Bachelor | 7 | 13% |
Professor > Associate Professor | 6 | 11% |
Student > Master | 4 | 7% |
Other | 5 | 9% |
Unknown | 11 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 16 | 29% |
Agricultural and Biological Sciences | 13 | 23% |
Immunology and Microbiology | 4 | 7% |
Engineering | 2 | 4% |
Environmental Science | 1 | 2% |
Other | 4 | 7% |
Unknown | 16 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2013.
All research outputs
#20,180,477
of 22,694,633 outputs
Outputs from Methods in molecular biology
#9,829
of 13,046 outputs
Outputs of similar age
#150,201
of 167,570 outputs
Outputs of similar age from Methods in molecular biology
#51
of 65 outputs
Altmetric has tracked 22,694,633 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,046 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,570 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.