Chapter title |
Metabolism of Triglyceride-Rich Lipoproteins.
|
---|---|
Chapter number | 520 |
Book title |
Prevention and Treatment of Atherosclerosis
|
Published in |
Handbook of experimental pharmacology, October 2021
|
DOI | 10.1007/164_2021_520 |
Pubmed ID | |
Book ISBNs |
978-3-03-086075-2, 978-3-03-086076-9
|
Authors |
Borén, Jan, Taskinen, Marja-Riitta |
Abstract |
Triglycerides are critical lipids as they provide an energy source that is both compact and efficient. Due to its hydrophobic nature triglyceride molecules can pack together densely and so be stored in adipose tissue. To be transported in the aqueous medium of plasma, triglycerides have to be incorporated into lipoprotein particles along with other components such as cholesterol, phospholipid and associated structural and regulatory apolipoproteins. Here we discuss the physiology of normal triglyceride metabolism, and how impaired metabolism induces hypertriglyceridemia and its pathogenic consequences including atherosclerosis. We also discuss established and novel therapies to reduce triglyceride-rich lipoproteins. |
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Demographic breakdown
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Mendeley readers
Geographical breakdown
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Unknown | 23 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 3 | 13% |
Student > Master | 3 | 13% |
Student > Doctoral Student | 2 | 9% |
Lecturer > Senior Lecturer | 1 | 4% |
Student > Bachelor | 1 | 4% |
Other | 0 | 0% |
Unknown | 13 | 57% |
Readers by discipline | Count | As % |
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Immunology and Microbiology | 1 | 4% |
Agricultural and Biological Sciences | 1 | 4% |
Other | 0 | 0% |
Unknown | 14 | 61% |