↓ Skip to main content

Pharmacology of the WNT Signaling System

Overview of attention for book
Pharmacology of the WNT Signaling System
Springer International Publishing
Attention for Chapter: Controlling Wnt Signaling Specificity and Implications for Targeting WNTs Pharmacologically.
Altmetric Badge

About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

twitter
3 X users

Readers on

mendeley
9 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Chapter title
Controlling Wnt Signaling Specificity and Implications for Targeting WNTs Pharmacologically.
Book title
Pharmacology of the WNT Signaling System
Published in
Handbook of experimental pharmacology, September 2021
DOI 10.1007/164_2021_529
Pubmed ID
Book ISBNs
978-3-03-085498-0, 978-3-03-085499-7
Authors

Sonavane, Pooja R, Willert, Karl, Sonavane, Pooja R.

Abstract

Wnt signaling is critical for proper development of the embryo and for tissue homeostasis in the adult. Activation of this signaling cascade is initiated by binding of the secreted Wnts to their receptors. With the mammalian genome encoding multiple Wnts and Wnt receptors, a longstanding question in the field has been how Wnt-receptor specificities are achieved. Emerging from these studies is a picture of exquisite control over Wnt protein production, secretion, distribution, and receptor interactions, culminating in activation of downstream signaling cascades that control a myriad of biological processes. Here we discuss mechanisms by which Wnt protein activities are tuned and illustrate how the multiple layers of regulation can be leveraged for therapeutic interventions in disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 11%
Other 1 11%
Student > Doctoral Student 1 11%
Unknown 6 67%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 11%
Agricultural and Biological Sciences 1 11%
Medicine and Dentistry 1 11%
Unknown 6 67%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 September 2021.
All research outputs
#13,749,545
of 23,310,485 outputs
Outputs from Handbook of experimental pharmacology
#332
of 650 outputs
Outputs of similar age
#191,034
of 429,594 outputs
Outputs of similar age from Handbook of experimental pharmacology
#4
of 17 outputs
Altmetric has tracked 23,310,485 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 650 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.5. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 429,594 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.