Report for: Natural Products Isolation

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Chapter title	Isolation of microbial natural products.
Chapter number	15
Book title	Natural Products Isolation
Published in	Methods in molecular biology, March 2012
DOI	10.1007/978-1-61779-624-1_15
Pubmed ID	22367905
Book ISBNs	978-1-61779-623-4, 978-1-61779-624-1
Authors	Olov Sterner
Abstract	In principle, the isolation of secondary metabolites from microbes does not differ from their isolation from other organisms. The extraction procedure may of course be quite different, especially if it is carried out in an industrial scale, but when an extract containing the metabolites of interest is at hand, it is the same palette of adsorbents and chromatographic techniques that provide the major tools for the fractionation and eventual isolation of the pure compounds. Compared to plants, in which one is sure to find secondary metabolites of certain types, e.g., flavonoids, microbes can be expected to produce virtually anything and it is important to go about the fractionation procedure with an open mind. This chapter presents an overview of preparation of extracts from microbial sources, and various methods and strategies involved in the isolation and characterization of microbial natural products.

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Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country	Count	As %
United States	2	3%
Indonesia	2	3%
Malaysia	1	1%
Mexico	1	1%
India	1	1%
Unknown	70	91%

Demographic breakdown

Readers by professional status	Count	As %
Researcher	16	21%
Student > Ph. D. Student	15	19%
Student > Bachelor	9	12%
Student > Master	7	9%
Student > Doctoral Student	5	6%
Other	16	21%
Unknown	9	12%

Readers by discipline	Count	As %
Agricultural and Biological Sciences	22	29%
Chemistry	15	19%
Pharmacology, Toxicology and Pharmaceutical Science	8	10%
Biochemistry, Genetics and Molecular Biology	8	10%
Medicine and Dentistry	4	5%
Other	10	13%
Unknown	10	13%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 November 2012.

All research outputs

#20,172,971

of 22,685,926 outputs

Outputs from Methods in molecular biology

#9,829

of 13,045 outputs

Outputs of similar age

#141,186

of 155,747 outputs

Outputs of similar age from Methods in molecular biology

#59

of 69 outputs

Altmetric has tracked 22,685,926 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.

So far Altmetric has tracked 13,045 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.

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We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.

Natural Products Isolation

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Mendeley readers

Geographical breakdown

Demographic breakdown

Attention Score in Context