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Biolistic DNA Delivery

Overview of attention for book
Cover of 'Biolistic DNA Delivery'

Table of Contents

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    Book Overview
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    Chapter 1 Comparison Between Agrobacterium -Mediated and Direct Gene Transfer Using the Gene Gun
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    Chapter 2 Transient Gene Expression in Epidermal Cells of Plant Leaves by Biolistic DNA Delivery
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    Chapter 3 Transformation of Nuclear DNA in Meristematic and Embryogenic Tissues
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    Chapter 4 Biolistic DNA Delivery to Leaf Tissue of Plants with the Non-vacuum Gene Gun (HandyGun)
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    Chapter 5 HandGun-Mediated Inoculation of Plants with Viral Pathogens for Mechanistic Studies
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    Chapter 6 Biolistics-Based Gene Silencing in Plants Using a Modified Particle Inflow Gun
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    Chapter 7 Biolistic Transformation of Caenorhabditis elegans
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    Chapter 8 Improved Vectors for Selection of Transgenic Caenorhabditis elegans
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    Chapter 9 Biolistic Transformation of Brugia Malayi
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    Chapter 10 Biolistic Transfection of Human Embryonic Kidney (HEK) 293 Cells
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    Chapter 11 Biolistic Transfection of Tumor Tissue Samples
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    Chapter 12 Biolistic Transfection of Freshly Isolated Adult Ventricular Myocytes
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    Chapter 13 Biolistic transfection of neurons in organotypic brain slices.
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    Chapter 14 Biolistic DNA Delivery to Mice with the Low Pressure Gene Gun
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    Chapter 15 Chemokine Overexpression in the Skin by Biolistic DNA Delivery
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    Chapter 16 Enhancement of Gene Gun-Induced Vaccine-Specific Cytotoxic T-Cell Response by Administration of Chemotherapeutic Drugs
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    Chapter 17 Dendritic Cell-Specific Biolistic Transfection Using the Fascin Gene Promoter
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    Chapter 18 Particle-Mediated Administration of Plasmid DNA on Corneas of BALB/c Mice
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    Chapter 19 Optimizing particle-mediated epidermal delivery of an influenza DNA vaccine in ferrets.
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    Chapter 20 Methods for Monitoring Gene Gun-Induced HBV- and HCV-Specific Immune Responses in Mouse Models
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    Chapter 21 Gene gun immunization to combat malaria.
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    Chapter 22 Identification of T Cell Epitopes of Mycobacterium tuberculosis with Biolistic DNA Vaccination
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    Chapter 23 Biolistic DNA vaccination against trypanosoma infection.
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    Chapter 24 Biolistic DNA Vaccination Against Melanoma
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    Chapter 25 Biolistic DNA Vaccination Against Cervical Cancer
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    Chapter 26 Efficiency of Biolistic DNA Vaccination in Experimental Type I Allergy
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    Chapter 27 Safety Assessment of Biolistic DNA Vaccination
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    Chapter 28 DiOlistics: Delivery of Fluorescent Dyes into Cells
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    Chapter 29 Protein Antigen Delivery by Gene Gun-Mediated Epidermal Antigen Incorporation (EAI)
Attention for Chapter 23: Biolistic DNA vaccination against trypanosoma infection.
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Chapter title
Biolistic DNA vaccination against trypanosoma infection.
Chapter number 23
Book title
Biolistic DNA Delivery
Published in
Methods in molecular biology, January 2013
DOI 10.1007/978-1-62703-110-3_23
Pubmed ID
Book ISBNs
978-1-62703-109-7, 978-1-62703-110-3
Authors

Marianne Bryan, Siobhan Guyach, Karen A. Norris, Bryan, Marianne, Guyach, Siobhan, Norris, Karen A.

Abstract

Immunization to protect against Trypanosoma cruzi infection has the potential to greatly decrease the burden of Chagas' disease in the Americas. Several target antigens have been explored by multiple investigators and show promise, but given that this parasite has multiple stages within the mammalian host, with both intracellular and extracellular forms, a multivalent vaccine will probably be necessary to provide complete immunity and prevent disease. Therefore, DNA immunization is an attractive method for efficient and effective delivery of multiple target antigens. In addition, the target population for a T. cruzi vaccine lives predominately in poorer rural areas in South America, making the stable DNA-gold precipitate, which does not require a cold-chain, used in biolistic immunization an attractive method for vaccination. Here we describe a biolistic immunization protocol that is capable of generating high titer antibody responses to recombinant T. cruzi vaccine targets and the in vitro preparation of T. cruzi for use in experimental vaccine challenge studies.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 1 20%
Unknown 4 80%
Readers by discipline Count As %
Immunology and Microbiology 1 20%
Unknown 4 80%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 November 2012.
All research outputs
#15,255,201
of 22,684,168 outputs
Outputs from Methods in molecular biology
#5,291
of 13,043 outputs
Outputs of similar age
#181,406
of 280,636 outputs
Outputs of similar age from Methods in molecular biology
#174
of 339 outputs
Altmetric has tracked 22,684,168 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,043 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
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We're also able to compare this research output to 339 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.