Chapter title |
Does Diet Matter? The Use of Polyunsaturated Fatty Acids (PUFAs) and Other Dietary Supplements in Inflammation-Associated Depression.
|
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Chapter number | 31 |
Book title |
Inflammation-Associated Depression: Evidence, Mechanisms and Implications
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Published in |
Current topics in behavioral neurosciences, July 2016
|
DOI | 10.1007/7854_2016_31 |
Pubmed ID | |
Book ISBNs |
978-3-31-951151-1, 978-3-31-951152-8
|
Authors |
Caitlín N. M. Hastings, Hannah Sheridan, Carmine M. Pariante, Valeria Mondelli |
Editors |
Robert Dantzer, Lucile Capuron |
Abstract |
An increasingly pertinent issue in psychiatry in recent years is that of the limitations of conventional antidepressants, which are not effective in a large number of patients with major depressive disorder (MDD). Coupled with emerging hypotheses about the role of inflammation in depression, it would appear that it is time to look for alternative treatments for these symptoms.This review will examine an emerging area in psychiatry, that of dietary supplements and the diet in general to treat depressive symptoms, and inflammation in depression. In particular, polyunsaturated fatty acids (PUFAs), probiotics and folic acid are three supplements that demonstrate the ability to target inflammation and other underlying systems in depression. While there is a definite need for more research in all these supplements to determine true efficacy, dosage and target populations, they can be used as mono- or adjunctive therapies to good effect, and show superior safety profiles when compared with more traditional alternatives. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 73 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 14% |
Student > Bachelor | 9 | 12% |
Other | 5 | 7% |
Researcher | 5 | 7% |
Student > Ph. D. Student | 5 | 7% |
Other | 10 | 14% |
Unknown | 29 | 40% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 12 | 16% |
Agricultural and Biological Sciences | 8 | 11% |
Nursing and Health Professions | 5 | 7% |
Neuroscience | 5 | 7% |
Psychology | 5 | 7% |
Other | 5 | 7% |
Unknown | 33 | 45% |